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Association details:
Biomarker:
ASNS underexpression
Cancer:
Ovarian Cancer
Drug:
IPN60090
(
Glutaminase inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Technology Networks
Title:
New Therapy for Lung and Ovarian Cancer Advances to Early-stage Clinical Development
Published date:
04/27/2020
Excerpt:
...low expression of the metabolic protein asparagine synthetase (ASNS) in ovarian cancers predicts response to IPN60090 in preclinical models.
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