^
Association details:
| Biomarker: | ASAP1 overexpression |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | temozolomide (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
EIF4A3-induced circular RNA ASAP1(circASAP1) promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1/2 signaling
Excerpt:
CircASAP1 expression was significantly up-regulated in recurrent GBM tissues and temozolomide-resistant cell lines.
DOI:
10.1093/neuonc/noaa214
