^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer

Published date:
08/19/2020
Excerpt:
...we treated a panel of PCa cell lines with specific DOT1L inhibitor EPZ004777, AR-positive CRPC cells (C42B), AR variant AR-V7 expressing cells (22Rv1) and ENZA resistant cells were all sensitive to DOT1L inhibitor.
DOI:
10.1038/s41467-020-18013-7