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Association details:
Biomarker:
AR positive
Cancer:
Urothelial Cancer
Drug:
silodosin
(
α1 adrenergic receptor antagonist
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
New
Source:
Am J Cancer Res
Title:
Effects of a 1-adrenergic receptor antagonists on the development and progression of urothelial cancer
Published date:
12/01/2020
Excerpt:
Similarly, cell proliferation/migration of AR-positive bladder cancer lines was considerably inhibited only by silodosin.
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