^
Association details:
| Biomarker: | ANIB1 overexpression |
|---|---|
| Cancer: | Pancreatic Ductal Adenocarcinoma |
| Drug: | GANT61 (Hedgehog cell-signalling pathway inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation
Published date:
01/01/2021
Excerpt:
In addition, we found PDAC cells with high AIB1 expression were also sensitive to GANT61, a GLI inhibitor, and they have a higher apoptotic rate than their counterparts with low AIB1 expression
DOI:
10.7150/thno.47390
