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Association details:
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
New
Title:

Remarkable Response to Crizotinib in Woman With Anaplastic Lymphoma Kinase–Rearranged Anaplastic Thyroid Carcinoma

Excerpt:
A 71-year-old woman...The gross examination of the surgical specimen revealed a 36 × 27 mm nonencapsulated nodule of the right thyroid lobe….we found ALK1 overexpression...we found a rearrangement of the ALK1 gene...CT examination at baseline (Fig 3A) and at 3 months after crizotinib (Fig 3B) showed an exceptional response of more than 90%...
DOI:
10.1200/JCO.2013.49.6596