^
Association details:
Biomarker:ALK rearrangement
Cancer:Non Small Cell Lung Cancer
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Source:
Title:

Spinal metastases from lung cancer: Survival depends only on genotype, neurological and personal status, scarcely of surgical resection

Excerpt:
818 lung SpM were diagnosed over the course or at the time of diagnosis of 210 consecutive patients with NSCLC….In univariate analysis, good World Health Organisation (WHO) status (p < 0.0001), ambulatory status (Frankel score) (p < 0.0001), the absence of spine epiduritis (p < 0.0001), immunotherapy after SpM diagnosis (p < 0.0001), ALK gene rearrangement (p < 0.0001) and EGFR mutation (p < 0.0001) were associated with longer survival...
DOI:
10.1016/j.suronc.2020.03.005