Patients were aged 18 years or older, had stage IIIb or stage IV ALK-positive NSCLC that had progressed while they were on crizotinib therapy....ALK fusion was detected at baseline in 75 (51%) of the 147 patients with assessable responses (table 4). 70 (93%) had an EML4–ALK fusion; variant 1 was the most frequent (table 4). The five non-EML4–ALK fusions were ALK–HIP1 (n=2), ALK–KIF5B (n=1), ALK–PPFIBP1 (n=1), and ALK–DCHS1 (n=1)....Table 4: Efficacy of ensartinib by ALK mutation type...