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Association details:
| Biomarker: | ALK G1123S |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | Zykadia (ceritinib) (ALK inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Identification of a Novel ALK G1123S Mutation in a Patient with ALK-rearranged Non–small-cell Lung Cancer Exhibiting Resistance to Ceritinib
Excerpt:
In summary, the G1123S mutation was identified in a patient with ALK+ non–small-cell lung cancer exhibiting resistance to ceritinib.
DOI:
10.1097/JTO.0000000000000509
