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Association details:
Biomarker:ALK fusion
Cancer:Lung Adenocarcinoma
Drug Class:ALK inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

[Ceritinib as First-line Treatment for Advanced Lung Adenocarcinoma with COX7A2L-ALK Fusion: A Case Report and Literature Review]

Published date:
04/20/2023
Excerpt:
...22 cases of rare ALK fusion were reported in 19 articles….The objective response rate (ORR) was 82.6% (19/23) and disease control rate (DCR) was 95.7% (22/23) for rare ALK fusions patients treated with ALK inhibitors. Lung adenocarcinoma patients with rare ALK fusion could benefit from ALK inhibitors.
DOI:
10.3779/j.issn.1009-3419.2023.102.15