^
Association details:
| Biomarker: | ALK A348D |
|---|---|
| Cancer: | Leukemia |
| Drug: | Zykadia (ceritinib) (ALK inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Therapeutically targetable ALK mutations in leukemia
Excerpt:
LDK378...inhibited ALK A348D cell growth with an IC50 of 22 nm and F856S cell growth with an IC50 of 4 nM.
DOI:
https://dx.doi.org/10.1158%2F0008-5472.CAN-14-1576
