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Association details:
| Biomarker: | AKR1C3 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | tamoxifen (Estrogen receptor antagonist) |
| Direction: | Resistant |
Evidence:
Source:
Title:
The role of AKR1 family in tamoxifen resistant invasive lobular breast cancer based on data mining
Published date:
12/09/2021
Excerpt:
Compared with TAM-sensitive counterparts, the expression levels of AKR1C1, AKR1C2, and AKR1C3 were up-regulated in TAM-resistant breast cancer cells.
DOI:
10.1186/s12885-021-09040-8
