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Association details:
Biomarker:
ADAMTS1 expression
Cancer:
Prostate Cancer
Drug:
docetaxel
(
Tubulin polymerization promoter
,
Microtubule stabilizer
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Front Oncol
Title:
The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer
Published date:
01/16/2023
Excerpt:
In mHSPC patients, expression of KLK2, KLK4, ADAMTS1, ZEB1 and SNAI1 was significantly associated with shorter OS and/or PFS.
DOI:
10.3389/fonc.2022.1060864
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