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Association details:
| Biomarker: | ADAM17 overexpression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | oxaliplatin (DNA synthesis inhibitor, DNA cross linking agent) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Long non-coding RNA MALAT1 regulates oxaliplatin-resistance via miR-324-3p/ADAM17 axis in colorectal cancer cells
Excerpt:
Significant up regulation of MALAT1 and ADAM17, and decrease of miR-324-3p were observed in Ox-resistant CRC tissues and cells.
DOI:
10.1186/s12935-020-01549-5
