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Association details:
Biomarker:
ACSM3 overexpression
Cancer:
Prostate Cancer
Drug:
erastin
(
Ferroptosis inducer
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
LCC 2021
Title:
ACSM1 and ACSM3 regulate fatty acid oxidation in prostate cancer to promote growth and protect against ferroptosis (#39)
Published date:
01/30/2021
Excerpt:
...over-expression of ACSM1 and ACSM3 elicited resistance to the ferroptosis inducers Erastin and ML21.
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