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Association details:
| Biomarker: | ACSM1 overexpression |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | ML210 (Ferroptosis inducer, Glutathione peroxidase 4 inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
ACSM1 and ACSM3 regulate fatty acid oxidation in prostate cancer to promote growth and protect against ferroptosis (#39)
Published date:
01/31/2021
Excerpt:
...over-expression of ACSM1 and ACSM3 elicited resistance to the ferroptosis inducers Erastin and ML21.
