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    Association details:
    Biomarker:ABCC2 overexpression
    Cancer:Breast Cancer
    Drug:paclitaxel (Tubulin inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    New
    Source:
    Toxicol Appl Pharmacol
    Title:

    Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters

    Excerpt:
    In paclitaxel-resistant MCF-7 cells, ABCB4/MDR3 and ABCC2/MRP2 proteins were up-regulated.
    DOI:
    10.1016/j.taap.2016.09.020