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Association details:
| Biomarker: | ABCC2 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | paclitaxel (Bcl2 inhibitor, Tubulin polymerization promoter) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters
Excerpt:
In paclitaxel-resistant MCF-7 cells, ABCB4/MDR3 and ABCC2/MRP2 proteins were up-regulated.
DOI:
10.1016/j.taap.2016.09.020
