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CANCER:
Thyroid Gland Anaplastic Carcinoma
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News alerts, weekly reports and conference planners
Related cancers:
‹
Thyroid Gland Carcinoma (359
)
Thyroid Gland Medullary Carcinoma (61
)
Thyroid Gland Papillary Carcinoma (58
)
Thyroid Gland Follicular Carcinoma (25
)
Thyroid Gland Hurthle Cell Carcinoma (12
)
Thyroid Gland Carcinoma (359
)
Thyroid Gland Medullary Carcinoma (61
)
Thyroid Gland Papillary Carcinoma (58
)
Thyroid Gland Follicular Carcinoma (25
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Thyroid Gland Hurthle Cell Carcinoma (12
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›
Associations
(70)
News
Trials
Search handles
@GautschiOliver
@PTarantinoMD
@StephenVLiu
@VivekSubbiah
@jamecancerdoc
@mihaela_aldea
@montypal
@rbryanbell
@weoncologists
Search handles
@GautschiOliver
@PTarantinoMD
@StephenVLiu
@VivekSubbiah
@jamecancerdoc
@mihaela_aldea
@montypal
@rbryanbell
@weoncologists
Filter by
Latest
10ms
@DrMCabanillas presenting on anaplastic thyroid cancer at #WCTC2023 in London. #thyroidcancer (@ThyroidCongress)
10 months ago
10ms
Ashok Shaha leading the anaplastic thyroid cancer panel including @DrMCabanillas, Peter Sadow, and others at #WCTC2023 in London. #thyroidcancer #anaplastic (@ThyroidCongress)
10 months ago
10ms
Kate Newbold, @DrMCabanillas, and Ashok Shaha speaking at the anaplastic thyroid cancer panel at #WCTC2023 in London. #thyroidcancer #anaplastic (@ThyroidCongress)
10 months ago
10ms
Really enjoyed this podcast with @ShepardDale and Dr Scharpf. I can talk to Dr Scharpf all day about anaplastic thyroid carcinoma, he is an amazing surgeon and colleague! @CleClinicHNI (@YilmazMDPhD)
10 months ago
10ms
Unlocking Treatment Strategies for Anaplastic Thyroid Cancer https://t.co/8P4gvwNrss via @clevelandclinic @YilmazMDPhD @ClevelandClinic (@jamecancerdoc)
10 months ago
10ms
This week on @CleClinicMD, Cancer Advances, @ShepardDale is joined by Joseph Scharpf, MD, FACS & @YilmazMDPhD. Tune in as they discuss unraveling treatment strategies and tumor characteristics of anaplastic thyroid cancer. https://t.co/E1u6MPz2nK #CleClinicCancer (@KatieRyba)
10 months ago
11ms
From a combination therapy for acute lymphoblastic leukemia to new insights into anaplastic thyroid cancer to a promising new treatment approach for pancreatic cancer, learn about the latest advances: https://t.co/Mjs8IJaXh6 @DrHKantarjian @JenniferWangMD @Dr_Di_Zhao #EndCancer (@MDAndersonNews)
11 months ago
Combination therapy
12ms
First win for #precisionmedicine in rare cancer patients from the ROAR trial 3/10👉 Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600–Mutant Anaplastic Thyroid Cancer @JCO_ASCO @ASCO lead to FDA approval in this deadly cancer #AACR23… https://t.co/lP5WSL0nDc (@VivekSubbiah)
12 months ago
Clinical • FDA event • Metastases
|
BRAF (B-raf proto-oncogene)
|
BRAF mutation • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
1year
Surgery After BRAF-Directed Therapy Is Associated with Improved Survival in BRAFV600E Mutant Anaplastic Thyroid Cancer: A Single-Center Retrospective Cohort Study | Thyroid https://t.co/l4qn8Im35x (@VivekSubbiah)
1 year ago
Retrospective data • Surgery
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
1year
Neoadjuvant BRAF-directed therapy in rare BRAF V600E+ anaplastic thyroid cancer--> downstaging with reduced surgery extent & morbidity, ⬆️PFS & OS irrespective of stage. 70% underwent surgery after Neoadj tt https://t.co/XmLAsjhIrJ (@mihaela_aldea)
1 year ago
Clinical • Surgery
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
1year
In 2018 Jan - Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600–Mutant Anaplastic Thyroid Cancer 2/7 @JCO_ASCO @ASCO @OncoAlert @Aiims1742 https://t.co/gMX386Ndzp (@VivekSubbiah)
1 year ago
Clinical • Metastases
|
BRAF (B-raf proto-oncogene)
|
BRAF mutation • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
1year
In 2018 May FDA approves dabrafenib plus trametinib for anaplastic thyroid cancer with BRAF V600E mutation 3/7 https://t.co/e8i1lxlh8g (@VivekSubbiah)
1 year ago
FDA event
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
1year
In 2022 we confirmed the definitive benefit - Dabrafenib + trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study 4/7 @Annals_Oncology @myESMO @OncoAlert https://t.co/HqtvJXyRRd (@VivekSubbiah)
1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
1year
Confirming the DEFINITIVE BENEFIT of Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer. First ever therapy for anaplastic thyroid cancer @Annals_Oncology @myESMO @OncoAlert https://t.co/B2cl6E0XFP (@VivekSubbiah)
1 year ago
Clinical
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
Anaplastic/undifferentiated thyroid carcinoma: ▫️Highly aggressive ▫️Preexisting well dif. carcinoma 22%-78% ▪️Current case: PTC tall cell pattern ▫️Pleomorphism, necrosis, mitosis ▫️#IHCPath high variability ▪️Current case: CK+, TTF1+, PAX8+, BerEP4- #EndoPath (@edusqo)
over 1 year ago
NKX2-1 (NK2 Homeobox 1) • PAX8 (Paired box 8)
over1year
Anaplastic thyroid carcinoma? Then you need to do BRAF mutation ASAP. https://t.co/ycoWsTam21 (@henryhmo)
over 1 year ago
BRAF (B-raf proto-oncogene)
|
BRAF mutation
over1year
Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600–Mutant Anaplastic Thyroid Cancer @JCO_ASCO https://t.co/Pg4JfKdaLR (@VivekSubbiah)
over 1 year ago
Clinical
|
BRAF (B-raf proto-oncogene)
|
BRAF mutation • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
UPDATED ROAR ANALYSIS CONFIRMS THE BENEFIT OF DABRAFENIB PLUS TRAMETINIB IN BRAF V600E–MUTATED ANAPLASTIC THYROID CANCER @myESMO https://t.co/rd4oI3GeUv (@VivekSubbiah)
over 1 year ago
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study https://t.co/B0N0ydTflX (@VivekSubbiah)
over 1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
⭐️Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @myESMO @Annals_Oncology @OncoAlert https://t.co/eZ6ueMDhG4 (@VivekSubbiah)
over 1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
⭐️Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study #PrecisionMedicine 🧬🎯 @Annals_Oncology @myESMO @OncoAlert https://t.co/5IZJ9gfazV (@VivekSubbiah)
over 1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
Circulating BRAF V600E Cell-Free DNA as a Biomarker in the Management of Anaplastic Thyroid Carcinoma @JCOPO_ASCO https://t.co/n2J81Kc1T9 (@VivekSubbiah)
over 1 year ago
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
over1year
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study https://t.co/64QpQX5prd (@VivekSubbiah)
over 1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
over1year
⭐️Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the ROAR basket study confirms the definitive benefit of BRAF+MEK in ATC with long-term follow-up @Annals_Oncology @myESMO @OncoAlert https://t.co/64QpQX5prd (@VivekSubbiah)
over 1 year ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
Nice case showing the utility of ultra rapid turn around time for BRAF mutation testing. Wow ! Impressive timeline ! 👏🏼. Would definitely benefit many aggressive cancers eg. Anaplastic thyroid cancer, or histiocytic neoplasms among many others. (@VivekSubbiah)
almost 2 years ago
BRAF (B-raf proto-oncogene)
|
BRAF mutation
almost2years
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @OncoAlert https://t.co/lWOXYDzylB (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
Here is the link to the open access paper 👉🏼 Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer @Annals_Oncology @OncoAlert @ADesaiMD https://t.co/ndPAXVhiVB (@VivekSubbiah)
almost 2 years ago
Clinical
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @OncoAlert https://t.co/mHYPCmUYxE (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
🎯🧬Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @OncoAlert https://t.co/32Bxn58vFb (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
💫Full final version online @Annals_Oncology Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study #precisionmedicine @myESMO #AACR22 @CD_AACR https://t.co/Smaw5aqBT4 (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology 2/5 https://t.co/NSOzs9DObV (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
almost2years
🎯🥁Our #precisionmedicine paper on BRAF+ MEK in Anaplastic thyroid cancer made it to Editor's choice articles in @Annals_Oncology @myESMO. Its open access to read @OncoAlert. Links to read & warm up before 1/5 #AACR22 https://t.co/Mo2rIobjSF (@VivekSubbiah)
almost 2 years ago
BRAF (B-raf proto-oncogene)
almost2years
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @myESMO https://t.co/8Xgwo7Btkn (@VivekSubbiah)
almost 2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
🎯Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study #PrecisionMedicine @Annals_Oncology @myESMO https://t.co/1gvuFL5mWY (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
Dedifferentiation Day 2! p16 and MTAP expression in anaplastic thyroid carcinoma! #uscap2022 (@RobHumbleMD)
2 years ago
MTAP (Methylthioadenosine Phosphorylase) • SKAP2 (Src Kinase Associated Phosphoprotein 2)
2years
⭐️🚨Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer👉🏼Lead to approval of combo. Updated analysis from the phase II 🦁 ROAR basket trial study confirms definitive benefit✅#PrecisionMedicine @Annals_Oncology @myESMO https://t.co/epEBLo3tZ9 (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
@MarkZafereoMD at #HNCS22 highlights anaplastic thyroid cancer is likely more than 1 disease with mutually exclusive BRAF and RET mutations. Promising combinations of BRAF and immunotherapy! trial coming to Cleveland Clinic @JLGeigerMD @YilmazMDPhD (@NeilWoodyMD)
2 years ago
IO biomarker
|
BRAF (B-raf proto-oncogene) • RET (Ret Proto-Oncogene)
|
BRAF mutation • RET mutation
2years
🚨Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @myESMO https://t.co/y4WGzpDARV (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
🚨Post-proof version online 👉Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer. Updated analysis from the phase II ROAR basket study confirms the definitive benefit @Annals_Oncology @myESMO @OncoAlert https://t.co/y4WGzpDARV (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
Dabrafenib plus trametinib in patients with BRAF V600E–mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @myESMO https://t.co/OZwRgU2NEx (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
⭐️Fully open access pre-proof version online 👉🏼Dabrafenib plus trametinib in patients with BRAF V600E–mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study @Annals_Oncology @myESMO @OncoAlert https://t.co/oQDaBGFQOn (@VivekSubbiah)
2 years ago
Clinical • Pan tumor
|
BRAF (B-raf proto-oncogene)
|
BRAF V600E • BRAF V600
|
Mekinist (trametinib) • Tafinlar (dabrafenib)
2years
FDA approves new uses for two drugs administered together for the treatment of BRAF-positive anaplastic thyroid cancer https://t.co/oshQBCbd4P (@VivekSubbiah)
2 years ago
FDA event
|
BRAF (B-raf proto-oncogene)
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