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CANCER:
Spindle Cell Sarcoma
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News alerts, weekly reports and conference planners
Related cancers:
‹
Sarcoma (668
)
Soft Tissue Sarcoma (443
)
Leiomyosarcoma (54
)
Osteosarcoma (54
)
Ewing Sarcoma (45
)
Fibrosarcoma (34
)
Rhabdomyosarcoma (34
)
Liposarcoma (25
)
Uterine Corpus Leiomyosarcoma (23
)
Kaposi Sarcoma (13
)
Neurofibrosarcoma (13
)
Sarcoma (668
)
Soft Tissue Sarcoma (443
)
Leiomyosarcoma (54
)
Osteosarcoma (54
)
Ewing Sarcoma (45
)
Fibrosarcoma (34
)
Rhabdomyosarcoma (34
)
Liposarcoma (25
)
Uterine Corpus Leiomyosarcoma (23
)
Kaposi Sarcoma (13
)
Neurofibrosarcoma (13
)
›
Associations
(100)
News
Trials
Search handles
@BenWestphalen
@VivekSubbiah
Search handles
@BenWestphalen
@VivekSubbiah
Filter by
Latest
9ms
Low grade fibromyxoid sarcoma (hyalinizing spindle cell tumor with giant rosettes)? MUC4? @JMGardnerMD ? (@VHNguyenMD)
9 months ago
MUC4 (Mucin 4, Cell Surface Associated)
9ms
Positive for malignancy, Mets if a spindle cell neoplasm (@deo_matovu_)
9 months ago
11ms
Spindle cell carcinoma (@Marytresa4)
11 months ago
12ms
Just learn that LPF-NT is now called NTRK-rearranged spindle cell tumor 🙈 I updated the DDx (@VHNguyenMD)
12 months ago
NTRK (Neurotrophic receptor tyrosine kinase)
1year
PLEOMORPHIC UNDIFFERENTIATED SPINDLE CELL SARCOMA. NOTE: THIS SARCOMA IS UNDIFFERENTIATED, I.E., IT DOES NOT SHOW A LINEAGE OF DIFFERENTIATION. THE LESIONAL CELLS ARE NEGATIVE FOR CK OSCAR, CK5/6, S100, CD34 AND DESMIN. A HIGH-GRADE MYXOFIBROSARCOMA IS A POTENTIAL CONSIDERATION. (@JacobSmalberger)
1 year ago
CD34 (CD34 molecule)
over1year
NTRK-rearranged spindle cell neoplasm (@TzuhangK)
over 1 year ago
NTRK (Neurotrophic receptor tyrosine kinase)
almost2years
Spindle cell tumour ntrk rearranged (@ashokparameswar)
almost 2 years ago
NTRK (Neurotrophic receptor tyrosine kinase)
almost2years
Hi Luca. Great cases, lots of thinking and loads of differentials. N°1: Spindle cell neoplasm, could be AFX, spindle cell melanoma, vascular tm, not sure IHC: SOX10, p40, Erg, CD34 N°2:Looks good for a benign neoplasm, Odontogenic myxoma my guess. Thanks for the tag. (@LoboAnandi)
almost 2 years ago
Clinical
|
CD34 (CD34 molecule) • SOX10 (SRY-Box 10)
almost2years
Ntrk-fusion spindle cell tumor Or other fusion involving alk, braf… (@BattistellaMD)
almost 2 years ago
BRAF (B-raf proto-oncogene) • NTRK (Neurotrophic receptor tyrosine kinase)
|
ALK fusion • NTRK fusion
almost2years
NTRK-rearranged spindle cell neoplasm? (@i_rg1993)
almost 2 years ago
NTRK (Neurotrophic receptor tyrosine kinase)
2years
Diagnosing uterine PEComas is incredibly difficult! Especially if you always limit your spindle cell neoplasm ddx to ESS and Leiomyosarcoma. #USCAP2022 @ISGynP (@lendeschwartz)
2 years ago
SKAP2 (Src Kinase Associated Phosphoprotein 2)
2years
Vimentin the intermediate filament didn’t do anything wrong. It’s just when #pathologists use (anti-) vimentin immunohistochemistry for classifying spindle cell tumors that I take issue! (@JMGardnerMD)
2 years ago
VIM (Vimentin)
2years
Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein | Journal of Hematology & Oncology @BMCMedicine https://t.co/OsioEhIfsA (@VivekSubbiah)
2 years ago
BRAF (B-raf proto-oncogene) • KIAA1549
|
KIAA1549-BRAF fusion • BRAF fusion
2years
Interesting #PrecisionOncology case report on a Spindle Cell Sarcoma with QKI-RAF1 Gene Fusion successfully treated w Trametinib. Paper in @asco @asco @JCOPO_ASCO @OncoAlert 🚨#PrecisionMedicine @VivekSubbiah @StefanFrohling https://t.co/vHkZwBG2NH (@BenWestphalen)
2 years ago
RAF1 (Raf-1 Proto-Oncogene Serine/Threonine Kinase)
|
Mekinist (trametinib)
over2years
I want to see the following: -Intradermal nodular fasciitis -acral fibroblastic spindle cell tumor with EWSR-SMAD3 fusion - plexiform fibrohistiocytic tumor (@HENRYY_MD)
over 2 years ago
SMAD3 (SMAD Family Member 3)
over2years
NTRK rearrangement spindle cell neoplasm? Pan-trk (@08HxwLtqK7ffD2F)
over 2 years ago
NTRK (Neurotrophic receptor tyrosine kinase)
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