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BIOMARKER:
PIK3R1 mutation
i
Other names:
PIK3R1, Phosphoinositide-3-Kinase Regulatory Subunit 1, Phosphatidylinositol 3-Kinase 85 KDa Regulatory Subunit Alpha, Phosphoinositide-3-Kinase, Regulatory Subunit 1 (Alpha), Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha, Phosphoinositide-3-Kinase Regulatory Subunit Alpha, PtdIns-3-Kinase Regulatory Subunit Alpha, PI3K Regulatory Subunit Alpha, PI3-Kinase Subunit P85-Alpha, GRB1, Phosphatidylinositol 3-Kinase, Regulatory Subunit, Polypeptide 1 (P85 Alpha), Phosphatidylinositol 3-Kinase
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Entrez ID:
5295
Related biomarkers:
Expression
Mutation
Others
‹
PIK3R1 overexpression (2)
PIK3R1 overexpression (2)
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Associations
(3)
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almost2years
We do not observe any significant effect/ enrichment of Akt/ PIK3CA mutation in prostate cancer. Interestingly in breast cancer activating mutations of PIK3CA are enriched in HR+HER2- disease, whereas PIK3R1 mutations are enriched in TNBC. (@Goutam_Chak)
almost 2 years ago
HER-2 (Human epidermal growth factor receptor 2) • PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) • PIK3R1 (Phosphoinositide-3-Kinase Regulatory Subunit 1)
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HER-2 negative • PIK3CA mutation • PIK3R1 mutation
almost2years
PIK3R1-mutation regulates Insulin-PI3K-glycolytic pathway in #prostatecancer. Our @CCR_AACR paper shows frequent oncogenic alteration of PIK3R1 in #mCRPC @DrPhilKantoff @subhiii_n @nikolausschultz @PCF_Science @MSKCancerCenter @MountsinaiUro https://t.co/9p2jT3OVdt (@Goutam_Chak)
almost 2 years ago
PIK3R1 (Phosphoinositide-3-Kinase Regulatory Subunit 1)
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PIK3R1 mutation
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