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CANCER:
Multiple Myeloma
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(423)
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@AaronGoodman33
@Abdallah81MD
@AkshaySharmaMD
@AlGarfall
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@AshAlizadeh
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@AtrashShebli
@AuclairDan
@BenDiamondMD
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@BiranNoa
@BldCancerDoc
@CarmemBonfim1
@CharuAggarwalMD
@ChelseaPinnix
@CyclingDoctor
@DrEmmaHolliday
@DrEmmaSearle
@DrGarethMorgan1
@DrMarcosdelima
@DrMiguelPerales
@DrNikitaMehra
@DrOlaLandgren
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@DrRaulCordoba
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@Dr_AmerZeidan
@Drjhoffmanmiami
@EhsanMalekMD
@EileenMBoyle
@End_myeloma
@EshaKaul1
@FrancescoMaura4
@GlopesMd
@GomezDLeonMD
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@HenrychihangFu1
@HiraSMian
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@JoshuaRichterMD
@MKD_BMT
@ManniMD1
@MediHumdani
@MeeraMohanMD
@MinnemaMonique
@Mohty_EBMT
@Myeloma_Doc
@NBahlis
@NagiSaghir
@NicoleKuderer
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@ProfPadhani
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@RamonGarciaSanz
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Filter by
Latest
8ms
And thanks to our many collaborators @WinshipAtEmory and elsewhere @ajaynookaMD @PariharCohen @nanostringtech @JKaufmanMD @EagleMyeloma @SagarLonialMD @MadhavDhodapka1 (@Hope34Me)
8 months ago
DAPK1 (Death Associated Protein Kinase 1)
8ms
@DrKrinaPatel is multi talented, now running a session on lymphoma CAR-T and presented some promising data on CD70 allo CAR-T in T cell lymphoma. This target may be used in #mmsm in future Hard disease and 2 pts cases with early promising results @DAVAOnc #DAVABermudaHeme (@HadidiSamer)
8 months ago
Clinical
|
CD70 (CD70 Molecule)
8ms
At #DAVABermudaHeme @DrKrinaPatel discussing the challenges and therapeutic potential of IL-15 monotherapy in immuno-oncology. Including potential applications as a precursor or bridge to CAR-T therapy for #myeloma. (@drkomanduri)
8 months ago
Immuno-oncology
|
IL15 (Interleukin 15)
8ms
“With t(4;14), there’s FGFR3, MMSET, IgH, and NSD2. Everything just seems like random letters and numbers strung together.” 🤣 Very much agree - thank goodness #MMsm docs like @andrew02114 are trying to figure out how to target t(4;14) beyond just bortezomib! (@DAVAOnc Bermuda) (@RahulBanerjeeMD)
8 months ago
FGFR3 (Fibroblast growth factor receptor 3) • NSD2 (Nuclear Receptor Binding SET Domain Protein 2)
|
bortezomib
8ms
Great @DAVAOnc Bermuda slide by @andrew02114 about cereblon modulation in #MMsm, grouped not by drug but by specific targets. Nice segway to @adamssperling’s work about TP53 mutations emerging with len but not with pom. Hopefully some day SPMs will be a thing of the past! (@RahulBanerjeeMD)
8 months ago
TP53 (Tumor protein P53) • CRBN (Cereblon)
|
TP53 mutation
8ms
Patients with myeloma, learn from @bdermanmd as he discusses MRD in multiple myeloma in patient-friendly language. https://t.co/iQOXGZrO8v #mmsm clonoSEQ is FDA-cleared to assess MRD in MM, CLL and B-ALL. For further info & test limitations: https://t.co/sE39cuZxFD (@clonoSEQ)
8 months ago
Clinical
|
clonoSEQ
8ms
👀 nothing 2000 mg/m2 Cy can’t fix! Including Parkinsonism after cilta-cel #MMsm following workup. Fascinating that 95% of T-cells after slug of Cy still CAR+, but still worked rapidly! Well-written @BloodJournal case by @MJFzeta @MarcelaMaus @OncSadr @andrew02114 et al! (@RahulBanerjeeMD)
8 months ago
SNAI2 (Snail Family Transcriptional Repressor 2)
|
Carvykti (ciltacabtagene autoleucel)
8ms
He did so much, not only for myeloma, but also for hematology in Spain. I hope that his fellows maintain his vision. #GraciasDrSanMiguel, @BrunoPaiva_UNAV @mvmateos #myeloma #msmm (@CaersJo)
8 months ago
8ms
Congratulations to @EAonc Myeloma Committee Chair @VincentRK, on this prestigious appointment @IMFmyeloma (@eaonc)
8 months ago
8ms
Congratulations 👏 @VincentRK 👏 on your appointment as Chairperson-Elect of the International Myeloma Foundation (@IMFmyeloma.) I look forward to working with you and continuing to bring hope to #myeloma patients. #mmsm (@NorthTxMSG)
8 months ago
Clinical
8ms
#EAOnc EQUATE EAA181 Effective Quadruplet Utilization After Tx Evaluation: Ph3 RCT NDMM Not Intended for Early ASCT [Activated: 10/27/20] PI= @myelomaMD https://t.co/qD26HMx3J8 #NCT04566328 #mmMRD #mmsm @eaonc @mweissmdphd @VincentRK @LynneWagnerPhD Wei Snyder Kostakoglu @mtmdphd (@mtmdphd)
8 months ago
8ms
Francesca Castro @fcastroRD and I discuss practical nutrition tips as well as common questions and myths around healthy dietary patterns @MSK_DeptOfMed @MSKCancerCenter @HealthtreeMM @IMFmyeloma @ASH_hematology https://t.co/w2d2qsQZta #mmsm #cancer #nutrition (@UrviShahMD)
8 months ago
Clinical
8ms
Introducing @MeeraMohanMD (@MedicalCollege): speaker at our 2023 Wisconsin Multiple Myeloma & Lymphoma Summit! We're excited for this session, make sure to attend August 26 in Milwaukee. ➡️LEARN MORE: https://t.co/EbFkMP5Kr8 #CME #Oncology #MultipleMyeloma #Lymphoma (@btfoundation)
8 months ago
CME
8ms
Just out @BloodAdvances 🚨 Our systematic review & meta-analysis of infections following bispecific antibodies in myeloma led by @GemmaKReynolds We look at infections in 1666 BsAb trial patients, including #ASH22 data 🧵👇 https://t.co/v9GBiGLybo #mmsm #EHA23 @ManniMD1 1/x (@Eddie_Cliff)
8 months ago
Retrospective data • Review
8ms
ICYMI: What's the current state of CAR-T access for MM? In this video from the myeloma roundtable series, @szusmani of @MSKCancerCenter; @YiLinMDPhD of @MayoClinic; Shambavi Richard, MD of @TischCancer; and @MeeraMohanMD of @MedicalCollege, weigh in. 📺: https://t.co/avUlp8bgVe (@Blood_Cancers)
8 months ago
Video
8ms
Our @NatureComms paper is published👉checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease👉new role of PD-1H in bone biology independent of its known immunoregulatory functions #mmsm @BMT_updates @columbiacancer https://t.co/HPEu4gmmuz (@SLentzsch)
8 months ago
Checkpoint inhibition
|
VSIR (V-Set Immunoregulatory Receptor)
8ms
Living with a #multiplemyeloma often requires patients to take up to four medications, as tolerated. In @healthcentral, our specialist @docbraunstein of @NYULISOM_HemOnc shares tips and resources from @theMMRF for patients managing combination therapy: https://t.co/RdXVYigsc7 (@Perlmutter_CC)
8 months ago
Clinical • Combination therapy
8ms
Agree, very interesting and much needed. Perhaps adding a hypomethylating agent to high risk myeloma treatment warrants reexamination since the demise of panabinostat. (@CamilleAbboud10)
8 months ago
8ms
Ph3 RCT Len vs Obs in SMM [10/25/19] @SagarLonialMD @SJ_OncBiostats @Rfonsi1 @mweissthedacare @myelomaMD @Myeloma_Doc @kaufman_MMdoc @AYACOUB7 Buadi, O’Brien @MileHighMyeloma Anderson et al. @VincentRK @JCO_ASCO https://t.co/J5KR4xhcPT #mmsm #EAonc E3A06 @eaonc #NCT01169337 (@mtmdphd)
8 months ago
8ms
. @SWOG S1803 Ph3 Len +/- Daratumumab/rhuph20 as Post-ASCT Maintenance in Myeloma Using Minimal Residual Disease (#mmMRD) to direct Therapy Duration (DRAMMATIC) - @DoctorAKrishnan Hoering, @Phari Sexton, @Myeloma_Doc #ASH20 Abst 1515 https://t.co/IeLcOehWrr #NCT04071457 #mmsm (@mtmdphd)
8 months ago
Clinical • Minimal residual disease
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Darzalex Faspro (daratumumab/hyaluronidase)
8ms
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd (@mtmdphd)
8 months ago
lenalidomide • Darzalex (daratumumab)
8ms
Factors in Selecting Therapy at First Relapse in #MultipleMyeloma https://t.co/VTo97HYKNh via @onclive With @JoshuaRichterMD and colleagues (@TischCancer)
8 months ago
8ms
Un lujo recibir a @mvmateos en la @fcvcolombia y aprender y conversar sobre #MultipleMyeloma (@JaiverFonseca)
8 months ago
8ms
Do NOT miss the opportunity to join IMF Chief Medical Officer, Dr. Joseph Mikhael @jmikhaelmd for a LIVE Facebook Q&A on July 26th. This is your chance to ask him YOUR #myeloma questions. Register NOW! https://t.co/OA9QvxiPsy #mmsm #myeloma (@IMFmyeloma)
8 months ago
8ms
Join us today at 5 PM ET as Dr Neil Love hosts a discussion with Dr Hans Lee and @szusmani over the integration of bispecific antibodies to manage multiple myeloma. Register at the link below. https://t.co/EEKulBtCDj (@DrNeilLove)
8 months ago
8ms
Great thread @mtmdphd on prior studies also showing lack of evidence for neutropenic diets #mmsm #bmtsm (@UrviShahMD)
8 months ago
8ms
Excited to participate in this session #IMS23 in Athens....both as an oral abstract presenter and moderator with @Mohty_EBMT @myelomaMD highlighting @ECRI_RESEARCH @MyelomaCanada @McMasteResearch @HamHealthSci research (@HiraSMian)
8 months ago
8ms
One of my mates - in his early sixties - bust his arm Greek wrestling of all things (always into marshal arts + a cancer ENT surgeon! Anyway, it’s myeloma which was diagnosed on that x-ray 4 transplants later (and all the rest in Covid) and he seems to be fine! Life’s amazing! (@Coolcmsc)
8 months ago
8ms
ASH might help. They helped back when i had to do a “practice improvement module” they did a vaccination incentive for myeloma patients, it was kind of cool. Feel like ASCO is more like the AMA, not sure whether theyre there for us or are helping to sell us up the river (@FGB86309474)
8 months ago
Clinical
9ms
Fatigue can have a big impact on daily life for people with #myeloma. Dr. Benjamin Derman @bdermanmd from @UCCancerCenter shares advice for managing this common issue. https://t.co/dCpzAe59PA #MMsm (@power4patients)
9 months ago
9ms
Fractionated initial infusion + booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell, for relapsed/refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study https://t.co/pGXNRC881K #mmsm #bmtsm @fdezdelarrea @ainitaoliver #mmsm (@Transplant_Doc)
9 months ago
Clinical • CAR T-Cell Therapy
|
cesnicabtagene autoleucel (ARI0002h)
9ms
Multiomic mapping of acquired chromosome 1 copy number and structural variants to identify therapeutic vulnerabilities in multiple myeloma @DrGarethMorgan1 #mmsm https://t.co/cBMi7TznlB (@Transplant_Doc)
9 months ago
9ms
What are common therapies, and when are they used in #myeloma care? @Ashley_Rosko1 of @OSUCCC_James reviews. https://t.co/R9w9kwrfKX #bloodcancer #MMsm (@power4patients)
9 months ago
9ms
📣 BREAKING NEWS 📣 The on-demand content of #ESHMM2023 is now freely available on our ESH eLearning Centre ➡️ https://t.co/FOc2nkMeFC 4th How to Diagnose and Treat MULTIPLE #MYELOMA Chairs: @H_Einsele, @IreneGhobrial, @mvmateos #ESHCONFERENCES #HAEMATOLOGY #HEMATOLOGY (@ESHaematology)
9 months ago
9ms
Natural history, predictors of development of extramedullary disease, and treatment outcomes for patients with extramedullary multiple myeloma https://t.co/S1NyR0q3vJ #mmsm @ZanwarSaurabh @myelomaMD @MayoMyeloma (@Transplant_Doc)
9 months ago
Clinical
9ms
#zksync #luckyfinance #presale https://t.co/aUhDu88kZQ #zksync, #luckyfinance, #Presale @AnikaNoniRose @FarOffGames @myelomaMD (@hooman_k101)
9 months ago
9ms
A @healthcentral central story on multiple myeloma symptoms. @HadidiSamer interviewed for this piece. https://t.co/SssFDK3Mfd #uamsmyeloma #uamscancer #uamshealth (@UAMSMyeloma)
9 months ago
Interview
9ms
ICYMI: In this video from the myeloma roundtable series, @szusmani of @MSKCancerCenter; @YiLinMDPhD of @MayoClinic; Shambavi Richard, MD of @TischCancer; and @MeeraMohanMD of @MedicalCollege, discuss maintenance therapy strategies for multiple myeloma. https://t.co/esR1qWfYb2 (@Blood_Cancers)
9 months ago
Clinical • Video
9ms
I know @majorajay did a similar project with myeloma in his youth – I think it would be an excellent idea to look into with lymphoma therapies as well! (@RahulBanerjeeMD)
9 months ago
9ms
Yes! We used the MMRF CoMMpass Registry: https://t.co/rmhas9f6Rf #mmsm (@majorajay)
9 months ago
9ms
Leading investigators in the multiple myeloma field discuss the latest clinical trial findings, many of which were presented during the 2023 ASCO Annual Meeting. @betsyodonnellmd @SusanBal9 @nsc_natalie @AlGarfall #mmsm https://t.co/0swx2NtFxs (@OncLive)
9 months ago
Clinical
9ms
Nothing about gain(1q) in #MMsm is ever simple, but glad to see so many cool teams working on unraveling its secrets in @CCR_AACR! All-star cast of authors including @EileenMBoyle @DrGarethMorgan1 @FrancescoMaura4 @DrOlaLandgren @docbraunstein @LouisWilliamsMD and more! (@RahulBanerjeeMD)
9 months ago
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