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BIOMARKER:
Inflammatory gene signature
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Associations
(2)
News
Trials
Search handles
@AaronGoodman33
@DrJNaidoo
Search handles
@AaronGoodman33
@DrJNaidoo
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Latest
2years
#ELCC22 Fascinating correlative science from NADIM trial of preop chemoIO in NSCLC: - 9 complete responders (CPR) v 5 non-complete - pro-inflammatory gene signature on pre-Tx tissue identifies CPRs - preTx IFNG, GZMB, NKG7, M1 macrophages could predict CPR @myesmo @Oncoalert (@DrJNaidoo)
2 years ago
IFNG (Interferon, gamma) • GZMB (Granzyme B)
|
Inflammatory gene signature
over2years
Duodenal Follicular Lymphoma Remarkably indolent! Almost never experience extra-intestinal dz t(14;18) positive Exclusively grade 1-2 ⬇️KMT2D mutations compared to nodal ⬆️ EEF1A1, ⬆️HVCN1 mutations Chronic inflammatory gene signature Key paper https://t.co/jFAtUiIJwv (@AaronGoodman33)
over 2 years ago
KMT2D (Lysine Methyltransferase 2D) • EEF1A1 (Eukaryotic Translation Elongation Factor 1 Alpha 1)
|
KMT2D mutation • Inflammatory gene signature
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