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    BIOMARKER:

    FGFR1 overexpression

    i
    Other names: FGFR1, BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM, Fibroblast growth factor receptor 1
    Entrez ID:
    2260
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    over1year
    We should also keep in mind that not all patients with HER2 alterations are responsive to HER2-based treatments. Previously, high expression of FGFR1 has been linked to shorter PFS in patients with HER2+ breast cancer. (@AyasunMDPhD)
    Clinical
    |
    HER-2 (Human epidermal growth factor receptor 2) • FGFR1 (Fibroblast growth factor receptor 1)
    |
    FGFR1 overexpression • FGFR1 expression
    almost3years
    Combined FGFR and Akt pathway inhibition abrogates growth of FGFR1 overexpressing EGFR-TKI-resistant NSCLC cells - Interesting and productive old collaboration (@AndresFCardonaZ)
    EGFR (Epidermal growth factor receptor) • FGFR1 (Fibroblast growth factor receptor 1)
    |
    EGFR overexpression • FGFR1 overexpression