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DRUG:
XL888
i
Other names:
XL888, EXEL-4888, XL-888, XL 888
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News alerts, weekly reports and conference planners
Associations
(2)
News
Trials
Company:
Exelixis, Merck (MSD)
Drug class:
HSP90 inhibitor
Related drugs:
‹
BMS-722782 (9)
AUY922 (7)
ADX-1612 (6)
pimitespib (5)
IPI-504 (5)
AT13387 (4)
LAM 003 (3)
IPI 493 (2)
aminoxyrone (1)
KW 2478 (0)
NCT-547 (0)
OS47701 (0)
RGRN-305 (0)
SNX-2112 (0)
SNX-5422 (0)
gamitrinib (0)
PEN-866 (0)
PU-H71 IV (0)
BMS-722782 (9)
AUY922 (7)
ADX-1612 (6)
pimitespib (5)
IPI-504 (5)
AT13387 (4)
LAM 003 (3)
IPI 493 (2)
aminoxyrone (1)
KW 2478 (0)
NCT-547 (0)
OS47701 (0)
RGRN-305 (0)
SNX-2112 (0)
SNX-5422 (0)
gamitrinib (0)
PEN-866 (0)
PU-H71 IV (0)
›
Associations
(2)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma (NCT02721459)
Phase 1
H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Resear...
Active, not recruiting
Phase 1
H. Lee Moffitt Cancer Center and Research Insti...
Active, not recruiting
Last update posted :
02/07/2025
Initiation :
09/07/2016
Primary completion :
10/31/2019
Completion :
03/01/2025
BRAF
|
BRAF mutation • BRAF V600
|
Zelboraf (vemurafenib) • Cotellic (cobimetinib) • XL888
Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma (NCT01657591)
Phase 1
H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Resear...
Completed
Phase 1
H. Lee Moffitt Cancer Center and Research Insti...
Completed
Last update posted :
01/19/2023
Initiation :
07/27/2012
Primary completion :
09/20/2016
Completion :
09/21/2021
BRAF
|
BRAF mutation • BRAF V600
|
Zelboraf (vemurafenib) • XL888
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