Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
DRUG CLASS:
VEGF-A inhibitor
DRUG CLASS:
VEGF-A inhibitor
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Related drugs:
‹
bevacizumab (416)
Aybintio (bevacizumab biosimilar) (14)
bevacizumab-maly (12)
bevacizumab-awwb (11)
bevacizumab-adcd (11)
bevacizumab-tnjn (8)
bevacizumab-bvzr (8)
aflibercept intravitreal (7)
bevacizumab-nwgd (7)
Byvasda (bevacizumab biosimilar) (4)
ziv-aflibercept IV (4)
BNT327 (2)
SIBP-04 (bevacizumab biosimilar) (1)
CTX-009 (1)
BP102 (bevacizumab biosimilar) (0)
SCT510 (bevacizumab biosimilar) (0)
Ankada (bevacizumab biosimilar) (0)
BI 695502 (bevacizumab biosimilar) (0)
MIL 60 (bevacizumab biosimilar) (0)
LY01008 (bevacizumab biosimilar) (0)
CBT124 (bevacizumab biosimilar) (0)
Cizumab (bevacizumab biosimilar) (0)
Equidacent (bevacizumab biosimilar) (0)
GB222 (bevacizumab biosimilar) (0)
GZ402663 (0)
HLX-04 (bevacizumab biosimilar) (0)
LYN-00101 (0)
ranibizumab (0)
MP0250 (0)
MSB0254 (0)
Onbevzi (bevacizumab biosimilar) (0)
PB101 (0)
Pusintin (bevacizumab biosimilar) (0)
TRS003 (bevacizumab biosimilar) (0)
HD204 (bevacizumab biosimilar) (0)
CLS-AX (0)
bevacizumab biosimilar (0)
hVEGF26–104/RFASE (0)
APX003 (0)
bevacizumab (416)
Aybintio (bevacizumab biosimilar) (14)
bevacizumab-maly (12)
bevacizumab-awwb (11)
bevacizumab-adcd (11)
bevacizumab-tnjn (8)
bevacizumab-bvzr (8)
aflibercept intravitreal (7)
bevacizumab-nwgd (7)
Byvasda (bevacizumab biosimilar) (4)
ziv-aflibercept IV (4)
BNT327 (2)
SIBP-04 (bevacizumab biosimilar) (1)
CTX-009 (1)
BP102 (bevacizumab biosimilar) (0)
SCT510 (bevacizumab biosimilar) (0)
Ankada (bevacizumab biosimilar) (0)
BI 695502 (bevacizumab biosimilar) (0)
MIL 60 (bevacizumab biosimilar) (0)
LY01008 (bevacizumab biosimilar) (0)
CBT124 (bevacizumab biosimilar) (0)
Cizumab (bevacizumab biosimilar) (0)
Equidacent (bevacizumab biosimilar) (0)
GB222 (bevacizumab biosimilar) (0)
GZ402663 (0)
HLX-04 (bevacizumab biosimilar) (0)
LYN-00101 (0)
ranibizumab (0)
MP0250 (0)
MSB0254 (0)
Onbevzi (bevacizumab biosimilar) (0)
PB101 (0)
Pusintin (bevacizumab biosimilar) (0)
TRS003 (bevacizumab biosimilar) (0)
HD204 (bevacizumab biosimilar) (0)
CLS-AX (0)
bevacizumab biosimilar (0)
hVEGF26–104/RFASE (0)
APX003 (0)
›
Associations
(506)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study Investigating the Efficacy and Safety of Ociperlimab and Tislelizumab and BAT1706 Combinations in Patients With Advanced HCC (AdvanTIG-206) (NCT04948697)
Phase 2
BeiGene
BeiGene
Completed
Phase 2
BeiGene
Completed
Last update posted :
02/24/2025
Initiation :
08/20/2021
Primary completion :
02/01/2024
Completion :
02/01/2024
PD-L1
|
PD-L1 expression
|
Tevimbra (tislelizumab-jsgr) • Avzivi (bevacizumab-tnjn) • ociperlimab (BGB-A1217)
Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer (ECOG-ACRIN 5103) (NCT00433511)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/20/2025
Initiation :
11/02/2007
Primary completion :
01/07/2014
Completion :
02/22/2025
HER-2 • ER
|
Avastin (bevacizumab) • paclitaxel • doxorubicin hydrochloride • cyclophosphamide • Aybintio (bevacizumab biosimilar) • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Avzivi (bevacizumab-tnjn) • Zirabev (bevacizumab-bvzr) • Airuituo (bevacizumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • Vasforda (bevacizumab biosimilar) • cyclophosphamide intravenous
SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer. (NCT06835179)
Phase 2
The First Affiliated Hospital with Nanjing Medical University
The First Affiliated Hospital with Nanj...
Not yet recruiting
Phase 2
The First Affiliated Hospital with Nanjing Medi...
Not yet recruiting
Last update posted :
02/19/2025
Initiation :
02/01/2025
Primary completion :
02/01/2027
Completion :
05/01/2027
BRAF
|
Avastin (bevacizumab) • Tevimbra (tislelizumab-jsgr) • capecitabine • oxaliplatin
Niraparib Versus Bevacizumab As Maintenance Therapy in Patients with De Novo Ovarian Cancer Without Homologous Recombination Deficiency (OVNI-B) (NCT06827353)
Phase N/A
Centre Hospitalier Universitaire de Nīmes
Centre Hospitalier Universitaire de Nīmes
Recruiting
Phase N/A
Centre Hospitalier Universitaire de Nīmes
Recruiting
Last update posted :
02/14/2025
Initiation :
10/01/2020
Primary completion :
05/31/2025
Completion :
09/30/2025
BRCA
|
Avastin (bevacizumab) • Zejula (niraparib)
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer (NCT00217737)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/14/2025
Initiation :
09/06/2005
Primary completion :
08/31/2025
Completion :
08/31/2025
MSI • MSH2
|
Avastin (bevacizumab) • 5-fluorouracil • oxaliplatin • leucovorin calcium • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Avzivi (bevacizumab-tnjn) • Zirabev (bevacizumab-bvzr) • Jobevne (bevacizumab-nwgd) • fluorouracil topical • Airuituo (bevacizumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • Vasforda (bevacizumab biosimilar)
A Three-arm Randomized Phase II Study of Dostarlimab Alone or with Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) (NCT06023862)
Phase 2
Yonsei University
Yonsei University
Recruiting
Phase 2
Yonsei University
Recruiting
Last update posted :
02/14/2025
Initiation :
01/22/2024
Primary completion :
08/31/2027
Completion :
12/31/2029
MSI • PD-1 • WT1
|
Avastin (bevacizumab) • gemcitabine • paclitaxel • doxorubicin hydrochloride • Jemperli (dostarlimab-gxly) • pegylated liposomal doxorubicin
Evaluating Novel Therapies in ctDNA Positive GI Cancers (MRD-GI) (NCT05482516)
Phase 3
Georgetown University
Georgetown University
Recruiting
Phase 3
Georgetown University
Recruiting
Last update posted :
02/13/2025
Initiation :
03/29/2023
Primary completion :
12/01/2026
Completion :
12/01/2028
CD4
|
Avastin (bevacizumab) • Tecentriq (atezolizumab)
Atezolizumab Plus Bevacizumab in First Line NSCLC Patients (TELMA) (NCT03836066)
Phase 2
Fundación GECP
Fundación GECP
Completed
Phase 2
Fundación GECP
Completed
Last update posted :
02/13/2025
Initiation :
05/15/2019
Primary completion :
10/21/2024
Completion :
10/21/2024
TMB
|
Avastin (bevacizumab) • Tecentriq (atezolizumab)
FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer (NCI-2022-09458) (NCT05627635)
Phase 1/2
City of Hope Medical Center
City of Hope Medical Center
Active, not recruiting
Phase 1/2
City of Hope Medical Center
Active, not recruiting
Last update posted :
02/12/2025
Initiation :
05/03/2023
Primary completion :
10/07/2025
Completion :
10/07/2025
POLE
|
POLE mutation
|
Avastin (bevacizumab) • oxaliplatin • leucovorin calcium • balstilimab (AGEN2034) • botensilimab (AGEN1181) • fluorouracil topical
PLATFORM Study of Precision Medicine for Rare Tumors (NCT04423185)
Phase 2
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Cancer Institute and Hospital, Chinese ...
Recruiting
Phase 2
Cancer Institute and Hospital, Chinese Academy ...
Recruiting
Last update posted :
02/11/2025
Initiation :
08/15/2020
Primary completion :
07/01/2026
Completion :
07/01/2028
EGFR • HER-2 • BRAF • ALK • MET • BRCA1 • BRCA2 • KIT • ROS1 • CDKN2A
|
BRCA2 mutation • BRCA1 mutation • EGFR mutation • HER-2 overexpression • BRAF mutation • HER-2 amplification • MET amplification • KIT mutation • ALK fusion • ROS1 fusion • CDKN2A mutation • MET mutation • BRAF amplification
|
Xalkori (crizotinib) • Tecentriq (atezolizumab) • Ibrance (palbociclib) • Zelboraf (vemurafenib) • imatinib • Tyvyt (sintilimab) • Alecensa (alectinib) • Zejula (niraparib) • Irene (pyrotinib) • Ameile (aumolertinib) • Vizimpro (dacomitinib)
ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+Bevacizumab (NCT02891824)
Phase 3
ARCAGY/ GINECO GROUP
ARCAGY/ GINECO GROUP
Completed
Phase 3
ARCAGY/ GINECO GROUP
Completed
Last update posted :
02/11/2025
Initiation :
09/22/2016
Primary completion :
10/15/2021
Completion :
02/22/2024
PD-L1
|
Avastin (bevacizumab) • Tecentriq (atezolizumab) • carboplatin • paclitaxel • doxorubicin liposomal
CAPOX + Bevacizumab + Tirelizumab Treating PDL1 CPS < 5 GEA (NCT05299476)
Phase 2
Chinese PLA General Hospital
Chinese PLA General Hospital
Recruiting
Phase 2
Chinese PLA General Hospital
Recruiting
Last update posted :
02/11/2025
Initiation :
04/16/2022
Primary completion :
01/20/2025
Completion :
06/01/2025
HER-2 • PD-L1
|
HER-2 negative
|
Avastin (bevacizumab) • Tevimbra (tislelizumab-jsgr) • capecitabine • oxaliplatin
BAT1308 Combined with Platinum-Based Chemotherapy± Bevacizumab for PDL1-Positive (CPS ≥1) Cervical Cancer (NCT06123884)
Phase 2/3
Bio-Thera Solutions
Bio-Thera Solutions
Recruiting
Phase 2/3
Bio-Thera Solutions
Recruiting
Last update posted :
02/10/2025
Initiation :
12/13/2023
Primary completion :
09/01/2026
Completion :
01/01/2027
PD-L1
|
PD-L1 expression
|
Avastin (bevacizumab) • cisplatin • carboplatin • paclitaxel • Avzivi (bevacizumab-tnjn) • BAT1308
Surgery Combined with Maintenance Targeted Therapy in the Treatment of Advanced Ovarian Cancer (NCT05200260)
Phase 2
Shanghai Gynecologic Oncology Group
Shanghai Gynecologic Oncology Group
Recruiting
Phase 2
Shanghai Gynecologic Oncology Group
Recruiting
Last update posted :
02/10/2025
Initiation :
07/13/2022
Primary completion :
06/01/2027
Completion :
06/01/2027
HRD • BRCA
|
HRD
|
Avastin (bevacizumab) • Lynparza (olaparib) • carboplatin • paclitaxel • docetaxel • Zejula (niraparib)
Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer (NCT03203525)
Phase 1
M.D. Anderson Cancer Center
M.D. Anderson Cancer Center
Recruiting
Phase 1
M.D. Anderson Cancer Center
Recruiting
Last update posted :
02/10/2025
Initiation :
06/23/2020
Primary completion :
12/31/2026
Completion :
12/31/2026
PIK3CA • PTEN
|
PIK3CA mutation
|
Avastin (bevacizumab) • 5-fluorouracil • oxaliplatin • Torisel (temsirolimus) • pegylated liposomal doxorubicin • leucovorin calcium • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Myocet (non-pegylated liposomal doxorubicin) • Duomeisu (pegylated liposomal doxorubicin) • fluorouracil topical • Airuituo (bevacizumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • Vasforda (bevacizumab biosimilar) • doxorubicin liposomal
Nab-P+Cb+PD1 Inhibitors Combined/not Combined with Bevacizumab As Neoadjuvant Therapy for Early TNBC (NCT06817525)
Phase 2
Henan Cancer Hospital
Henan Cancer Hospital
Recruiting
Phase 2
Henan Cancer Hospital
Recruiting
Last update posted :
02/10/2025
Initiation :
11/06/2024
Primary completion :
11/06/2025
Completion :
11/06/2025
CD8 • PD-1 • VEGFA • CD4 • FGF • GZMB • TGFB1 • CD31 • PECAM1
|
Avastin (bevacizumab) • carboplatin • AiRuiKa (camrelizumab)
Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery (NCT02884648)
Phase 2
M.D. Anderson Cancer Center
M.D. Anderson Cancer Center
Active, not recruiting
Phase 2
M.D. Anderson Cancer Center
Active, not recruiting
Last update posted :
02/07/2025
Initiation :
11/15/2016
Primary completion :
02/01/2026
Completion :
02/01/2026
MUC16
|
Avastin (bevacizumab)
Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer (NCT01081262)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/06/2025
Initiation :
10/12/2010
Primary completion :
02/25/2015
Completion :
03/01/2025
KRAS
|
KRAS mutation
|
Avastin (bevacizumab) • carboplatin • paclitaxel • capecitabine • oxaliplatin • Aybintio (bevacizumab biosimilar) • Vegzelma (bevacizumab-adcd) • Avzivi (bevacizumab-tnjn)
Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed by Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery (CALGB 40603) (NCT00861705)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/06/2025
Initiation :
05/15/2009
Primary completion :
08/01/2014
Completion :
02/22/2025
HER-2 • ER • PGR
|
HER-2 negative
|
Avastin (bevacizumab) • carboplatin • paclitaxel • doxorubicin hydrochloride • cyclophosphamide • Aybintio (bevacizumab biosimilar) • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Avzivi (bevacizumab-tnjn) • Zirabev (bevacizumab-bvzr) • Airuituo (bevacizumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • Vasforda (bevacizumab biosimilar) • cyclophosphamide intravenous
Treatment Strategies in Colorectal Cancer Patients with Initially Unresectable Liver-only Metastases (CAIRO5) (NCT02162563)
Phase 3
Dutch Colorectal Cancer Group
Dutch Colorectal Cancer Group
Completed
Phase 3
Dutch Colorectal Cancer Group
Completed
Last update posted :
02/06/2025
Initiation :
07/01/2014
Primary completion :
07/01/2022
Completion :
01/01/2025
BRAF • RAS
|
BRAF mutation • RAS mutation
|
Avastin (bevacizumab) • 5-fluorouracil • Vectibix (panitumumab) • oxaliplatin • irinotecan • leucovorin calcium
Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC (NCT04958811)
Phase 2
Georgetown University
Georgetown University
Recruiting
Phase 2
Georgetown University
Recruiting
Last update posted :
02/06/2025
Initiation :
12/21/2021
Primary completion :
12/01/2025
Completion :
12/01/2025
ALK • ROS1
|
PD-L1 expression • ALK wild-type • ROS1 wild-type
|
Avastin (bevacizumab) • Tecentriq (atezolizumab) • tiragolumab (RG6058)
Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer (NCT02138617)
Phase 2
UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center
Completed
Phase 2
UNC Lineberger Comprehensive Cancer Center
Completed
Last update posted :
02/06/2025
Initiation :
05/01/2014
Primary completion :
08/01/2024
Completion :
08/01/2024
UGT1A1
|
UGT1A1*1*1
|
Avastin (bevacizumab) • 5-fluorouracil • irinotecan • leucovorin calcium • Mvasi (bevacizumab-awwb)
Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer (CALGB-40503) (NCT00601900)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/06/2025
Initiation :
09/24/2008
Primary completion :
06/30/2014
Completion :
05/30/2025
ER • PGR
|
ER expression
|
Avastin (bevacizumab) • letrozole • Aybintio (bevacizumab biosimilar) • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Avzivi (bevacizumab-tnjn) • Zirabev (bevacizumab-bvzr) • Airuituo (bevacizumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • Soltamox (tamoxifen citrate) • Vasforda (bevacizumab biosimilar)
A Phase III Study of Bevacizumab and Paclitaxel in Combination with Atezolizumab As a Treatment for Locally Advanced Unresectable or Metastatic Hormone Receptor-positive HER2 Negative Breast Cancer (AMBITION) (NCT04732598)
Phase 3
Japanese Foundation for Cancer Research
Japanese Foundation for Cancer Research
Active, not recruiting
Phase 3
Japanese Foundation for Cancer Research
Active, not recruiting
Last update posted :
02/05/2025
Initiation :
01/21/2021
Primary completion :
09/30/2025
Completion :
09/30/2025
HER-2 • PD-L1
|
HR positive • HER-2 negative
|
Avastin (bevacizumab) • Tecentriq (atezolizumab) • paclitaxel
Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab (NCT01814501)
Phase 2
John Hays
John Hays
Completed
Phase 2
John Hays
Completed
Last update posted :
02/05/2025
Initiation :
02/01/2013
Primary completion :
08/06/2018
Completion :
08/06/2018
KRAS
|
KRAS mutation • NRAS mutation • RAS mutation
|
Avastin (bevacizumab) • 5-fluorouracil • Vectibix (panitumumab) • irinotecan • leucovorin calcium
Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients (NCT05468359)
Phase 1/2
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
Recruiting
Phase 1/2
St. Jude Children's Research Hospital
Recruiting
Last update posted :
02/04/2025
Initiation :
11/07/2022
Primary completion :
06/01/2032
Completion :
06/01/2037
PD-L1
|
Avastin (bevacizumab) • Tecentriq (atezolizumab) • sorafenib • cyclophosphamide
Sequential Treatment Strategy for Metastatic Colorectal Cancer (ITACa) (NCT01878422)
Phase 3
Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori
Istituto Scientifico Romagnolo per lo S...
Completed
Phase 3
Istituto Scientifico Romagnolo per lo Studio e ...
Completed
Last update posted :
01/31/2025
Initiation :
11/01/2007
Primary completion :
03/01/2014
Completion :
06/11/2016
KRAS
|
Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • oxaliplatin • irinotecan • leucovorin calcium
Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer (NCT05999812)
Phase 2
University of Texas Southwestern Medical Center
University of Texas Southwestern Medica...
Recruiting
Phase 2
University of Texas Southwestern Medical Center
Recruiting
Last update posted :
01/29/2025
Initiation :
12/19/2023
Primary completion :
10/01/2026
Completion :
10/01/2028
BRAF • MSI • MLH1 • MSH6 • MSH2 • CD4
|
BRAF V600E • BRAF V600 • RAS wild-type
|
Avastin (bevacizumab) • Tecentriq (atezolizumab)
Study of Bevacizumab in Combination with Chemoimmunotherapy and Atezolizumab in Patients with Extensive Stage Small Cell Lung Cancer and Liver Metastases (BELIEVE) (NCT05588388)
Phase 2
Kamya Sankar
Kamya Sankar
Recruiting
Phase 2
Kamya Sankar
Recruiting
Last update posted :
01/22/2025
Initiation :
07/15/2024
Primary completion :
12/28/2026
Completion :
12/28/2027
EGFR
|
EGFR mutation
|
Avastin (bevacizumab) • Tecentriq (atezolizumab) • carboplatin
A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer (Liberty-201) (NCT05609370)
Phase 1/2
BeiGene
BeiGene
Active, not recruiting
Phase 1/2
BeiGene
Active, not recruiting
Last update posted :
01/01/2025
Initiation :
01/29/2023
Primary completion :
04/15/2026
Completion :
04/15/2026
PD-L1
|
PD-L1 expression
|
Avastin (bevacizumab) • 5-fluorouracil • Tevimbra (tislelizumab-jsgr) • capecitabine • Avzivi (bevacizumab-tnjn) • alcestobart (LBL-007)
A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC (NCT03511963)
Phase 3
Shanghai Henlius Biotech
Shanghai Henlius Biotech
Completed
Phase 3
Shanghai Henlius Biotech
Completed
Last update posted :
12/31/2024
Initiation :
04/09/2018
Primary completion :
04/15/2020
Completion :
04/20/2023
BRAF
|
Avastin (bevacizumab) • 5-fluorouracil • capecitabine • oxaliplatin • leucovorin calcium • Hanbeitai (bevacizumab biosimilar)
Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study (Better Brain) (NCT06728865)
Phase 2
Li-kun Chen
Li-kun Chen
Recruiting
Phase 2
Li-kun Chen
Recruiting
Last update posted :
12/11/2024
Initiation :
09/04/2024
Primary completion :
02/01/2028
Completion :
02/01/2028
EGFR
|
EGFR mutation
|
Avastin (bevacizumab) • Ivesa (firmonertinib)
Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab (NCT02436993)
Phase 2
University of California, Irvine
University of California, Irvine
Active, not recruiting
Phase 2
University of California, Irvine
Active, not recruiting
Last update posted :
12/09/2024
Initiation :
04/01/2015
Primary completion :
06/01/2025
Completion :
06/01/2025
HER-2
|
HER-2 positive • HER-2 negative
|
Avastin (bevacizumab) • Herceptin (trastuzumab) • carboplatin • paclitaxel • Perjeta (pertuzumab)
A Study of PM8002 Plus Nab-paclitaxel as First Line Therapy for TNBC (PM8002-B004C-TNBC-R) (NCT05918133)
Phase 1/2
Biotheus Inc.
Biotheus Inc.
Recruiting
Phase 1/2
Biotheus Inc.
Recruiting
Last update posted :
12/03/2024
Initiation :
07/01/2022
Primary completion :
10/30/2026
Completion :
10/30/2026
HER-2 • PGR
|
HER-2 negative • ER negative
|
albumin-bound paclitaxel • BNT327
Safety and Efficacy of Pembrolizumab in Combination with Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer (NCT06550453)
Phase 4
yangjianjun
yangjianjun
Recruiting
Phase 4
yangjianjun
Recruiting
Last update posted :
11/12/2024
Initiation :
09/01/2024
Primary completion :
01/15/2025
Completion :
01/15/2026
BRAF
|
Keytruda (pembrolizumab) • Avastin (bevacizumab) • capecitabine • oxaliplatin
Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney Cancer (NCI-2012-01247) (NCT01684397)
Phase 1/2
Roswell Park Cancer Institute
Roswell Park Cancer Institute
Active, not recruiting
Phase 1/2
Roswell Park Cancer Institute
Active, not recruiting
Last update posted :
11/06/2024
Initiation :
11/21/2012
Primary completion :
05/02/2025
Completion :
05/02/2025
CXCL8
|
Avastin (bevacizumab) • pazopanib
A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib (NCT02873962)
Phase 2
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Active, not recruiting
Phase 2
Dana-Farber Cancer Institute
Active, not recruiting
Last update posted :
10/30/2024
Initiation :
11/10/2016
Primary completion :
01/01/2025
Completion :
01/01/2027
BRCA
|
BRCA mutation
|
Opdivo (nivolumab) • Avastin (bevacizumab) • Rubraca (rucaparib)
NEoadjuvant Olaparib Combination OvArian Cancer Targeted Study (NEOCATS) (NCT06650709)
Phase 2
British Columbia Cancer Agency
British Columbia Cancer Agency
Not yet recruiting
Phase 2
British Columbia Cancer Agency
Not yet recruiting
Last update posted :
10/23/2024
Initiation :
11/01/2024
Primary completion :
05/01/2026
Completion :
11/01/2028
BRCA
|
Avastin (bevacizumab) • Lynparza (olaparib) • Imfinzi (durvalumab)
A Clinical Study to Evaluate Efficacy and Safety of Serplulimab(HLX10) Combined With Bevacizumab(HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC) (ASTRUM-015) (NCT04547166)
Phase 2/3
Shanghai Henlius Biotech
Shanghai Henlius Biotech
Recruiting
Phase 2/3
Shanghai Henlius Biotech
Recruiting
Last update posted :
10/17/2024
Initiation :
03/10/2021
Primary completion :
09/24/2025
Completion :
12/30/2026
PD-L1
|
PD-L1 expression
|
Avastin (bevacizumab) • capecitabine • oxaliplatin • Hetronifly (serplulimab) • Hanbeitai (bevacizumab biosimilar)
Hyperpolarized 13C-MRI in Patients with Hepatocellular Carcinoma Undergoing Radiotherapy, Atezolizumab, and Bevacizumab (NCT06605664)
Phase 2
Chang Gung Memorial Hospital
Chang Gung Memorial Hospital
Not yet recruiting
Phase 2
Chang Gung Memorial Hospital
Not yet recruiting
Last update posted :
09/24/2024
Initiation :
09/30/2024
Primary completion :
06/30/2029
Completion :
09/30/2031
ITGAM
|
Avastin (bevacizumab) • Tecentriq (atezolizumab)
"cindilizumab + Bevacizumab + Coenzyme I for Injection" in Unresectable Hepatocellular Carcinoma (NCT06590844)
Phase 4
Anhui Provincial Hospital
Anhui Provincial Hospital
Active, not recruiting
Phase 4
Anhui Provincial Hospital
Active, not recruiting
Last update posted :
09/11/2024
Initiation :
12/19/2023
Primary completion :
03/01/2026
Completion :
03/01/2026
PD-L1
|
Avastin (bevacizumab) • Tyvyt (sintilimab)
Share
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login