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    BIOMARKER:

    STAT3 mutation

    i
    Other names: STAT3, Signal Transducer And Activator Of Transcription 3, Acute-Phase Response Factor , APRF, Signal Transducer And Activator Of Transcription 3 (Acute-Phase Response Factor), DNA-Binding Protein APRF, ADMIO1, ADMIO, HIES
    Entrez ID:
    6774
    Related biomarkers:
    Expression
    Mutation
    Others
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    Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia (NCT05592015)
    Phase 2
    Ohio State University Comprehensive Cancer Center
    Not yet recruiting
    Last update posted :
    10/24/2022
    Initiation :
    12/01/2022
    Primary completion :
    12/31/2024
    Completion :
    12/31/2025
    CD8 • STAT3 • B3GAT1
    |
    STAT3 mutation
    |
    Jakafi (ruxolitinib)
    Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia (T-LGLL) (NCT05141682)
    Phase 1/2
    Jonathan Brammer
    Recruiting
    Last update posted :
    04/25/2022
    Initiation :
    05/01/2022
    Primary completion :
    12/31/2024
    Completion :
    12/31/2025
    CD8 • STAT3 • IL15
    |
    STAT3 mutation
    |
    Onureg (azacitidine oral) • Invega Sustenna (paliperidone palmitate extended-release 1-month injection)