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DRUG CLASS:
Ribonucleotide reductase inhibitor
DRUG CLASS:
Ribonucleotide reductase inhibitor
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News alerts, weekly reports and conference planners
Related drugs:
‹
hydroxyurea (3)
3-AP (1)
NSC-324360 (1)
imexon (0)
COH29 (0)
TAS1553 (0)
motexafin gadolinum (0)
hydroxyurea (3)
3-AP (1)
NSC-324360 (1)
imexon (0)
COH29 (0)
TAS1553 (0)
motexafin gadolinum (0)
›
Associations
(5)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors (ETCTN 10388) (NCT04234568)
Phase 1
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 1
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
06/13/2024
Initiation :
07/20/2020
Primary completion :
12/01/2024
Completion :
12/01/2024
SSTR
|
SSTR Expression
|
Lutathera (lutetium Lu 177 dotatate) • Triapine (3-AP)
Role of BMP Pathway in MDS Progression (BMP-MDS) (NCT06175923)
Phase N/A
Hospices Civils de Lyon
Hospices Civils de Lyon
Not yet recruiting
Phase N/A
Hospices Civils de Lyon
Not yet recruiting
Last update posted :
01/23/2024
Initiation :
01/27/2024
Primary completion :
01/27/2029
Completion :
01/27/2034
BMP2 • BMP4
|
azacitidine • hydroxyurea
Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML (GFM-DAC-CMML) (NCT02214407)
Phase 3
Groupe Francophone des Myelodysplasies
Groupe Francophone des Myelodysplasies
Completed
Phase 3
Groupe Francophone des Myelodysplasies
Completed
Last update posted :
11/19/2021
Initiation :
10/14/2014
Primary completion :
07/05/2021
Completion :
08/16/2021
ABL1 • BCR
|
decitabine • hydroxyurea
MRI for Detecting Cancer in Women Who Are at High Risk of Developing Breast Cancer (NCT00003736)
Phase N/A
Abramson Cancer Center of the University of Pennsylvania
Abramson Cancer Center of the Universit...
Completed
Phase N/A
Abramson Cancer Center of the University of Pen...
Completed
Last update posted :
09/24/2019
Initiation :
06/01/1999
Primary completion :
06/01/2002
Completion :
06/01/2002
BRCA1 • BRCA2
|
BRCA2 mutation • BRCA1 mutation
|
Xcytrin (motexafin gadolinum)
A Randomized Study of Amplimexon (Imexon) With Gemcitabine in Pancreatic Cancer (NCT00637247)
Phase 2
AmpliMed Corporation
AmpliMed Corporation
Completed
Phase 2
AmpliMed Corporation
Completed
Last update posted :
03/20/2019
Initiation :
04/01/2008
Primary completion :
05/01/2010
Completion :
06/01/2010
G6PD
|
gemcitabine • Amplimexon (imexon)
Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia (FAST) (NCT02611973)
Phase 3
Assistance Publique - Hôpitaux de Paris
Assistance Publique - Hôpitaux de Paris
Recruiting
Phase 3
Assistance Publique - Hôpitaux de Paris
Recruiting
Last update posted :
07/26/2017
Initiation :
03/10/2016
Primary completion :
11/01/2019
Completion :
11/01/2022
JAK2 • CALR
|
JAK2 V617F • CALR mutation
|
hydroxyurea • aspirin
Primary Thrombocythaemia 1 Trial (NCT00175838)
Phase N/A
University of Cambridge
University of Cambridge
Completed
Phase N/A
University of Cambridge
Completed
Last update posted :
01/18/2017
Initiation :
07/01/1997
Primary completion :
11/01/2016
Completion :
11/01/2016
ABL1 • BCR
|
hydroxyurea • aspirin
Imexon for Relapsed Follicular and Aggressive Lymphomas (NCT01314014)
Phase 2
University of Rochester
University of Rochester
Completed
Phase 2
University of Rochester
Completed
Last update posted :
01/06/2016
Initiation :
05/01/2011
Primary completion :
03/01/2013
Completion :
08/01/2014
G6PD
|
Amplimexon (imexon)
Treatment of CML Patients With Imatinib and Hydroxyurea (CML2004) (NCT02480608)
Phase 1/2
University of Leipzig
University of Leipzig
Completed
Phase 1/2
University of Leipzig
Completed
Last update posted :
06/24/2015
Initiation :
04/01/2004
Primary completion :
08/01/2011
Completion :
05/01/2013
ABL1 • BCR
|
imatinib • hydroxyurea
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