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BIOMARKER:

RAD54L mutation

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Other names: DNA Repair And Recombination Protein RAD54, RAD54 Homolog, RAD54A, HRAD54, HHR54, RAD54 Like (S. Cerevisiae), RAD54 (S.Cerevisiae)-Like
Entrez ID:
Related biomarkers:
Phase 1/2
National Cancer Institute (NCI)
Not yet recruiting
Last update posted :
08/02/2021
Initiation :
08/05/2021
Primary completion :
03/01/2026
Completion :
03/01/2026
BRCA2 • BRCA1 • HRD • CDK12 • RAD51B • BRIP1 • CHEK2 • RAD51C • CHEK1 • RAD51D • RAD54L • BRCA • BARD1 • FANCL • PPP2R2A
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BRCA1 mutation • ATM mutation • PALB2 mutation • CDK12 mutation • BRIP1 mutation • CHEK2 mutation • RAD51C mutation • RAD51D mutation • RAD51B mutation • RAD54L mutation • BARD1 mutation • CHEK1 mutation • CHEK1 expression
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Trodelvy (sacituzumab govitecan-hziy) • berzosertib (M6620)
Phase 2
West Cancer Center
Not yet recruiting
Last update posted :
07/30/2021
Initiation :
08/01/2021
Primary completion :
08/01/2024
Completion :
08/01/2025
BRCA2 • BRCA1 • HRD • CDK12 • RAD51B • BRIP1 • CHEK2 • RAD51C • CHEK1 • RAD51D • RAD54L • BARD1 • FANCI • FANCL • PPP2R2A
|
BRCA1 mutation • ATM mutation • HRD • PALB2 mutation • BRIP1 mutation • CHEK2 mutation • RAD51C mutation • RAD51D mutation • HRD + BRCA1 mutation • RAD51B mutation • RAD54L mutation • BARD1 mutation • FANCI mutation • RAD51 mutation
|
Zejula (niraparib) • Jemperli (dostarlimab)
Phase 2
Keunchil Park
Not yet recruiting
Last update posted :
06/25/2021
Initiation :
06/30/2021
Primary completion :
12/31/2022
Completion :
12/31/2022
BRCA2 • BRCA1 • RAD51B • SLFN11 • RAD51 • RAD51C • RAD50 • RAD54L • BRCA • RAD52 • RECQL5 • WRN • NBN • RECQL • RECQL4 • RPA1
|
BRCA1 mutation • BRCA2 mutation • RAD51C mutation • RAD51D mutation • MRE11A mutation • RAD50 mutation • RAD51B mutation • RAD54L mutation • BLM mutation • BRCA mutation • NBN mutation • RAD52 mutation • RECQL mutation • RECQL4 mutation • RECQL5 mutation
|
Avastin (bevacizumab) • Lynparza (olaparib)
Phase 2
Shadia Jalal, MD
Recruiting
Last update posted :
04/13/2021
Initiation :
07/09/2019
Primary completion :
05/01/2021
Completion :
05/01/2022
BRCA2 • BRCA1 • ARID1A • CDK12 • FANCA • RAD51B • BRIP1 • CHEK2 • RAD51 • RAD51C • RAD51D • RAD54L • BARD1 • NBN • GEN1
|
BRCA1 mutation • BRCA2 mutation • ATM mutation • PALB2 mutation • CDK12 mutation • BRIP1 mutation • CHEK2 mutation • FANCA mutation • RAD51C mutation • RAD51D mutation • RAD51B mutation • RAD54L mutation • BARD1 mutation • NBN mutation
|
Zejula (niraparib)
Phase 2
Sidney Kimmel Comprehensive Cancer Center at Jo...
Recruiting
Last update posted :
03/15/2021
Initiation :
06/03/2019
Primary completion :
03/01/2022
Completion :
03/01/2023
BRCA2 • BRCA1 • BAP1 • CDK12 • RAD51B • BRIP1 • CHEK2 • RAD51C • CHEK1 • RAD51D • RAD54L • BARD1 • FANCL
|
BRCA1 mutation • ATM mutation • PALB2 mutation • CDK12 mutation • BRIP1 mutation • CHEK2 mutation • RAD51C mutation • RAD51D mutation • RAD51B mutation • RAD54L mutation • BARD1 mutation • CHEK1 mutation • RAD51 mutation • CHEK1 expression
|
Lynparza (olaparib)
Phase 2
Samsung Medical Center
Completed
Last update posted :
02/18/2021
Initiation :
08/01/2016
Primary completion :
01/01/2021
Completion :
01/01/2021
BRCA2 • BRCA1 • ATM • RAD51B • RAD51 • RAD51C • RAD50 • RAD54L • RAD52 • RECQL5 • WRN • NBN • RECQL • RECQL4 • RPA1
|
BRCA1 mutation • BRCA2 mutation • RAD51C mutation • RAD51D mutation • MRE11A mutation • RAD50 mutation • RAD51B mutation • RAD54L mutation • BLM mutation • WRN mutation • NBN mutation • RAD52 mutation • RECQL mutation • RECQL4 mutation • RECQL5 mutation • RPA1 mutation
|
Lynparza (olaparib)