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    DRUG:

    Rina-S (rinatabart sesutecan)

    i
    Other names: PRO1184, GEN1184, GEN-1184
    Company:
    Genmab
    Drug class:
    Topoisomerase I inhibitor, Folate receptor 1-targeted antibody-drug conjugate
    Related drugs:
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    PRO1184 for Advanced Solid Tumors (PRO1184-001) (NCT05579366)
    Phase 1/2
    ProfoundBio US Co.
    Recruiting
    Last update posted :
    05/03/2024
    Initiation :
    12/07/2022
    Primary completion :
    10/01/2025
    Completion :
    04/01/2026
    HER-2 • FOLR1
    |
    HR positive • HER-2 negative • FOLR1 expression • HR positive + HER-2 negative • PTEN mutation + HR positive
    |
    Keytruda (pembrolizumab) • Avastin (bevacizumab) • carboplatin • Rina-S (rinatabart sesutecan)