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BIOMARKER:
PPM1D mutation
i
Other names:
PPM1D, Protein Phosphatase Mg2+/Mn2+ Dependent 1D, Protein Phosphatase 1D Magnesium-Dependent Delta Isoform, Wild-Type P53-Induced Phosphatase 1, Protein Phosphatase 1D, WIP1, Protein Phosphatase Magnesium-Dependent 1 Delta, Protein Phosphatase Mg2+/Mn2+ Dependent 1D, Protein Phosphatase 2C Delta Isoform, Protein Phosphatase 2C Delta Isoform, Protein Phosphatase 2C Isoform Delta, P53-Induced Protein Phosphatase 1, Protein Phosphatase Wip1, PP2C-DELTA, PP2C-Delta, IDDGIP, JDVS 3
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Entrez ID:
8493
Associations
(3)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer (NEO) (NCT02489006)
Phase 2
University Health Network, Toronto
University Health Network, Toronto
Active, not recruiting
Phase 2
University Health Network, Toronto
Active, not recruiting
Last update posted :
01/17/2024
Initiation :
07/19/2016
Primary completion :
12/31/2025
Completion :
12/31/2025
BRCA1 • BRCA2 • PALB2 • RAD51B • BRIP1 • RAD51C • PARP1 • RAD51D • BARD1 • PPM1D • FANCM
|
BRCA2 mutation • BRCA1 mutation • PALB2 mutation • BRIP1 mutation • RAD51C mutation • RAD51D mutation • RAD51B mutation • BARD1 mutation • PPM1D mutation • FANCM mutation • RAD51 mutation
|
Lynparza (olaparib)
Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer (NCT03654716)
Phase 1
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Completed
Phase 1
Dana-Farber Cancer Institute
Completed
Last update posted :
08/11/2023
Initiation :
11/01/2018
Primary completion :
07/17/2023
Completion :
07/17/2023
TP53 • MDM2 • TET2 • SMARCB1 • PPM1D
|
TP53 wild-type • MDM2 amplification • TET2 mutation • SMARCA4 mutation • PPM1D mutation
|
cytarabine • ALRN-6924
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