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BIOMARKER:
PML-RARA fusion
i
Other names:
PML, Promyelocytic Leukemia, Tripartite Motif-Containing Protein 19, Promyelocytic Leukemia Protein, RING Finger Protein 71, Protein PML, PP8675, TRIM19, RNF71, MYL, Promyelocytic Leukemia, Inducer Of, Probable Transcription Factor PML, Tripartite Motif Protein TRIM19, PML/RARA Fusion, RARA, Retinoic Acid Receptor Alpha, Nuclear Receptor Subfamily 1 Group B Member 1, RAR-Alpha, NR1B1, Nucleophosmin-Retinoic Acid Receptor Alpha Fusion Protein NPM-RAR Long Form, Retinoic Acid Nuclear Receptor Alph
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Entrez ID:
5914
;
5371
Related biomarkers:
Expression
Fusion
Others
‹
›
Associations
(5)
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Trials
Phase
Status
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Phase
Status
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Phase III Trial in Acute Promyelocytic Leukemia Patients (APL0406) (NCT00482833)
Phase 3
Gruppo Italiano Malattie EMatologiche dell'Adulto
Gruppo Italiano Malattie EMatologiche d...
Completed
Phase 3
Gruppo Italiano Malattie EMatologiche dell'Adulto
Completed
Last update posted :
10/11/2022
Initiation :
08/01/2007
Primary completion :
09/01/2012
Completion :
10/17/2019
PML
|
PML-RARA fusion • Chr t(15;17) • Chr t(15;17)/PML-RARA fusion
|
idarubicin hydrochloride • arsenic trioxide • mercaptopurine
Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia (TUD-APOLLO-064) (NCT02688140)
Phase 3
Technische Universität Dresden
Technische Universität Dresden
Active, not recruiting
Phase 3
Technische Universität Dresden
Active, not recruiting
Last update posted :
08/05/2022
Initiation :
06/01/2016
Primary completion :
01/01/2025
Completion :
01/01/2025
PML
|
PML-RARA fusion • Chr t(15;17) • Chr t(15;17)/PML-RARA fusion
|
cytarabine • idarubicin hydrochloride • mitoxantrone • arsenic trioxide • mercaptopurine • Invega Sustenna (paliperidone palmitate extended-release 1-month injection)
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