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DRUG:
plixorafenib (FORE-8394)
i
Other names:
FORE-8394, PLX 8394, PLX-8394, PLX8394, FORE8394, FORE 8394
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Associations
(20)
News
Trials
Company:
Daiichi Sankyo, Fore Biotherap
Drug class:
BRAF inhibitor, BRAF V600E inhibitor
Related drugs:
‹
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
avutometinib (27)
ERAS-254 (7)
RAF265 (7)
GDC 0879 (6)
RXDX-105 (5)
RAF709 (3)
BGB-3245 (1)
HI-511 (1)
SB-590885 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BMS-908662 (0)
PF-07799933 (0)
S241656 (0)
encorafenib (63)
ABM-1310 (5)
CB-006-3 (1)
RX208 (0)
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
avutometinib (27)
ERAS-254 (7)
RAF265 (7)
GDC 0879 (6)
RXDX-105 (5)
RAF709 (3)
BGB-3245 (1)
HI-511 (1)
SB-590885 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BMS-908662 (0)
PF-07799933 (0)
S241656 (0)
encorafenib (63)
ABM-1310 (5)
CB-006-3 (1)
RX208 (0)
›
Associations
(20)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations (NCT05503797)
Phase 2
Fore Biotherapeutics
Fore Biotherapeutics
Recruiting
Phase 2
Fore Biotherapeutics
Recruiting
Last update posted :
02/17/2025
Initiation :
02/21/2023
Primary completion :
06/27/2025
Completion :
08/28/2026
BRAF
|
BRAF V600E • BRAF V600
|
plixorafenib (FORE-8394) • Tybost (cobicistat)
Feasibility of CSF and Plasma ctDNA in BRAF-altered Glioma During Treatment With Plixorafenib (NCT06610682)
Phase 1
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sidney Kimmel Comprehensive Cancer Cent...
Active, not recruiting
Phase 1
Sidney Kimmel Comprehensive Cancer Center at Jo...
Active, not recruiting
Last update posted :
01/13/2025
Initiation :
01/10/2025
Primary completion :
12/31/2026
Completion :
05/15/2027
BRAF
|
plixorafenib (FORE-8394) • Tybost (cobicistat)
A Study of FORE8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors (NCT02428712)
Phase 1/2
Fore Biotherapeutics
Fore Biotherapeutics
Active, not recruiting
Phase 1/2
Fore Biotherapeutics
Active, not recruiting
Last update posted :
04/09/2024
Initiation :
04/01/2015
Primary completion :
05/01/2024
Completion :
12/01/2024
BRAF
|
BRAF mutation
|
plixorafenib (FORE-8394)
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