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    BIOMARKER:

    PIK3CA Q546

    i
    Entrez ID:
    5290
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    Apply
    Study of PIK3CA Mutations and Effectiveness and Tolerability Outcomes of Alpelisib in Real-world (SPEAR) (NCT05022342)
    Phase N/A
    Novartis Pharmaceuticals
    Recruiting
    Last update posted :
    07/07/2023
    Initiation :
    10/27/2021
    Primary completion :
    09/30/2025
    Completion :
    09/30/2025
    HER-2 • ER • PIK3CA • PGR
    |
    HR positive • HER-2 negative • PIK3CA mutation • PIK3CA H1047R • PIK3CA E545K • PIK3CA E545 • PIK3CA E542 • PIK3CA H1047L • PIK3CA C420R • PIK3CA E545A • PIK3CA E545G • PIK3CA Q546 • PIK3CA Q546R
    |
    Piqray (alpelisib) • fulvestrant
    Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer (NRG-GY008) (NCT02728258)
    Phase 2
    NRG Oncology
    Completed
    Last update posted :
    02/15/2022
    Initiation :
    09/16/2016
    Primary completion :
    08/18/2018
    Completion :
    02/14/2020
    PIK3CA
    |
    PIK3CA mutation • PIK3CA H1047R • PIK3CA E545K • PIK3CA E545 • PIK3CA E542 • PIK3CA H1047L • PIK3CA M1043I • PIK3CA C420R • PIK3CA E545A • PIK3CA N345K • PIK3CA E545G • PIK3CA E545X • PIK3CA G1049R • PIK3CA H1047X • PIK3CA Q546 • PIK3CA Q546K • PIK3CA Q546R
    |
    Aliqopa (copanlisib)