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DRUG:
palazestrant (OP-1250)
i
Other names:
OP-1250
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News alerts, weekly reports and conference planners
Associations
(7)
News
Trials
Company:
Olema Pharma
Drug class:
Estrogen receptor antagonist, Selective estrogen receptor degrader
Related drugs:
‹
tamoxifen (107)
AZD9833 (7)
GDC-9545 (4)
Z-endoxifen hydrochloride (2)
fulvestrant (57)
elacestrant (9)
SAR439859 (9)
imlunestrant (7)
SCR-6852 (4)
ZN-c5 (3)
AZD9496 (2)
GDC-0927 (2)
G1T48 (2)
LX-039 (1)
SCR6106 (1)
D-0502 (1)
AND019 (0)
DZD3969 (0)
LSZ102 (0)
SHR9549 (0)
GDC-0810 (0)
EGL-5385-C-1701 (0)
tamoxifen (107)
AZD9833 (7)
GDC-9545 (4)
Z-endoxifen hydrochloride (2)
fulvestrant (57)
elacestrant (9)
SAR439859 (9)
imlunestrant (7)
SCR-6852 (4)
ZN-c5 (3)
AZD9496 (2)
GDC-0927 (2)
G1T48 (2)
LX-039 (1)
SCR6106 (1)
D-0502 (1)
AND019 (0)
DZD3969 (0)
LSZ102 (0)
SHR9549 (0)
GDC-0810 (0)
EGL-5385-C-1701 (0)
›
Associations
(7)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Phase 1b Combo w/ Ribociclib, Alpelisib, or Everolimus (OP-1250-003) (NCT05508906)
Phase 1
Olema Pharmaceuticals, Inc.
Olema Pharmaceuticals, Inc.
Recruiting
Phase 1
Olema Pharmaceuticals, Inc.
Recruiting
Last update posted :
10/03/2024
Initiation :
08/31/2022
Primary completion :
05/20/2026
Completion :
06/30/2026
HER-2
|
HER-2 negative
|
everolimus • Piqray (alpelisib) • Kisqali (ribociclib) • palazestrant (OP-1250)
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer (OPERA-01) (NCT06016738)
Phase 3
Olema Pharmaceuticals, Inc.
Olema Pharmaceuticals, Inc.
Recruiting
Phase 3
Olema Pharmaceuticals, Inc.
Recruiting
Last update posted :
05/31/2024
Initiation :
11/16/2023
Primary completion :
06/30/2026
Completion :
09/30/2027
HER-2 • ER
|
HER-2 negative • ESR1 mutation
|
fulvestrant • letrozole • anastrozole • exemestane • palazestrant (OP-1250)
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