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DRUG:
onalespib (AT13387)
i
Other names:
AT13387, AT13387X, AT 13387, AT-13387
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Associations
(4)
News
Trials
Company:
Otsuka
Drug class:
HSP90 inhibitor
Related drugs:
‹
BMS-722782 (9)
AUY922 (7)
ADX-1612 (6)
pimitespib (5)
IPI-504 (5)
LAM 003 (3)
IPI 493 (2)
XL888 (2)
aminoxyrone (1)
KW 2478 (0)
NCT-547 (0)
OS47701 (0)
RGRN-305 (0)
SNX-2112 (0)
SNX-5422 (0)
gamitrinib (0)
PEN-866 (0)
PU-H71 IV (0)
BMS-722782 (9)
AUY922 (7)
ADX-1612 (6)
pimitespib (5)
IPI-504 (5)
LAM 003 (3)
IPI 493 (2)
XL888 (2)
aminoxyrone (1)
KW 2478 (0)
NCT-547 (0)
OS47701 (0)
RGRN-305 (0)
SNX-2112 (0)
SNX-5422 (0)
gamitrinib (0)
PEN-866 (0)
PU-H71 IV (0)
›
Associations
(4)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors (NCT00878423)
Phase 1
Astex Pharmaceuticals, Inc.
Astex Pharmaceuticals, Inc.
Completed
Phase 1
Astex Pharmaceuticals, Inc.
Completed
Last update posted :
01/18/2020
Initiation :
05/01/2008
Primary completion :
05/01/2013
Completion :
03/01/2014
HER-2
|
HER-2 positive
|
onalespib (AT13387)
AT13387 in Adults With Refractory Solid Tumors (NCT01246102)
Phase 1
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 1
National Cancer Institute (NCI)
Completed
Last update posted :
07/05/2018
Initiation :
11/19/2010
Primary completion :
12/30/2013
Completion :
10/27/2017
HSP90AA1
|
onalespib (AT13387)
A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib (NCT01712217)
Phase 1/2
Astex Pharmaceuticals, Inc.
Astex Pharmaceuticals, Inc.
Completed
Phase 1/2
Astex Pharmaceuticals, Inc.
Completed
Last update posted :
01/19/2018
Initiation :
10/01/2012
Primary completion :
12/01/2016
Completion :
05/16/2017
ALK
|
ALK mutation
|
Xalkori (crizotinib) • onalespib (AT13387)
AT13387 in Treating Patients With Refractory Solid Tumors (NCT01245218)
Phase 1
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Recruiting
Phase 1
National Cancer Institute (NCI)
Recruiting
Last update posted :
10/31/2017
Initiation :
11/01/2010
Primary completion :
08/01/2011
HER-2 • HSP90AA1
|
onalespib (AT13387)
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