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BIOMARKER:
NTRK1 mutation
i
Other names:
NTRK1, MTC, TRK, TRKA, Neurotrophic tyrosine kinase, receptor, type 1
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Entrez ID:
4914
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
›
Associations
(3)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma (NCT03556228)
Phase 1
VM Oncology, LLC
VM Oncology, LLC
Recruiting
Phase 1
VM Oncology, LLC
Recruiting
Last update posted :
05/31/2024
Initiation :
06/08/2018
Primary completion :
12/01/2025
Completion :
06/01/2026
NTRK1
|
NTRK1 fusion • NTRK1 mutation • NTRK expression
|
VMD-928
A Study of DB-1311 in Advanced/Metastatic Solid Tumors (NCT05914116)
Phase 1/2
DualityBio Inc.
DualityBio Inc.
Recruiting
Phase 1/2
DualityBio Inc.
Recruiting
Last update posted :
09/12/2023
Initiation :
09/05/2023
Primary completion :
04/01/2025
Completion :
04/01/2025
EGFR • KRAS • BRAF • ALK • MET • ROS1 • NTRK1 • NTRK3 • NTRK2 • CD276
|
BRAF V600E • KRAS mutation • EGFR mutation • KRAS G12C • BRAF V600 • NTRK1 fusion • NTRK3 fusion • NTRK2 fusion • ALK rearrangement • MET exon 14 mutation • ROS1 rearrangement • MET mutation • RET rearrangement • KRAS G12 • NTRK1 mutation • NTRK3 mutation
|
BNT324
A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies (APT-CUBE) (NCT05473156)
Phase 1/2
AP Biosciences Inc.
AP Biosciences Inc.
Not yet recruiting
Phase 1/2
AP Biosciences Inc.
Not yet recruiting
Last update posted :
02/03/2023
Initiation :
02/01/2023
Primary completion :
12/01/2026
Completion :
12/01/2027
BRAF • MET • NTRK1 • NTRK3 • NTRK2
|
PD-L1 expression • BRAF V600E • BRAF V600 • NTRK1 fusion • NTRK3 fusion • NTRK2 fusion • MET mutation • RET rearrangement • NTRK1 mutation • NTRK3 mutation
|
AP203
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