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BIOMARKER:
MYCN expression
i
Other names:
MYCN, MYCN Proto-Oncogene BHLH Transcription Factor, V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog, Class E Basic Helix-Loop-Helix Protein 37, N-Myc Proto-Oncogene Protein, BHLHe37, NMYC, Neuroblastoma-Derived V-Myc Avian Myelocytomatosis Viral Related Oncogene, Neuroblastoma MYC Oncogene, Oncogene NMYC, BHLHE37, MODED, N-Myc, ODED
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Entrez ID:
4613
Related biomarkers:
Expression
CNA
Others
‹
›
Associations
(1)
News
Trials
Phase
Status
Apply
Phase
Status
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Trial of CUDC-907 in Children and Young Adults with Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma (NCT02909777)
Phase 1
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Active, not recruiting
Phase 1
Dana-Farber Cancer Institute
Active, not recruiting
Last update posted :
02/13/2025
Initiation :
10/01/2016
Primary completion :
06/01/2025
Completion :
06/01/2025
MYC • MYCN
|
MYCN expression
|
fimepinostat (CUDC-907)
Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma (NCT01798004)
Phase 1
Children's Oncology Group
Children's Oncology Group
Active, not recruiting
Phase 1
Children's Oncology Group
Active, not recruiting
Last update posted :
03/13/2024
Initiation :
04/08/2013
Primary completion :
07/28/2015
MYCN
|
MYCN amplification • MYCN expression
|
cisplatin • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • vincristine • topotecan • melphalan • mesna • busulfan • Neupogen (filgrastim) • cyclophosphamide intravenous
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors (NCT01505569)
Phase N/A
Masonic Cancer Center, University of Minnesota
Masonic Cancer Center, University of Mi...
Completed
Phase N/A
Masonic Cancer Center, University of Minnesota
Completed
Last update posted :
02/26/2024
Initiation :
10/20/2011
Primary completion :
02/01/2024
Completion :
02/01/2024
MYCN • CD34
|
LDH elevation • MYCN expression
|
cisplatin • carboplatin • paclitaxel • ifosfamide • etoposide IV • melphalan • mesna • thiotepa • busulfan
An Intermediate Expanded Use Trial of DFMO (NCT03581240)
Phase N/A
Giselle Sholler
Giselle Sholler
Available
Phase N/A
Giselle Sholler
Available
Last update posted :
09/28/2023
MYCN
|
MYCN amplification • MYCN expression
Biomarkers in Blood and Tissue Samples From Patients With Newly Diagnosed Neuroblastoma (NCT01387724)
Phase N/A
Children's Oncology Group
Children's Oncology Group
Completed
Phase N/A
Children's Oncology Group
Completed
Last update posted :
05/18/2016
Initiation :
06/01/2011
Primary completion :
05/01/2016
NTRK2 • MYCN • BDNF
|
MYCN amplification • MYCN expression • NTRK expression
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