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    DRUG:

    mitoxantrone

    i
    Company:
    Generic mfg.
    Drug class:
    Topoisomerase II inhibitor
    Related drugs:
    Apply
    Phase II Study of the Combination of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin (MEGO) for Patients With Acute Myeloid Leukemia Refractory to Initial Standard Induction Therapy (NCT03839446)
    Phase 2
    Robert Redner, MD
    Completed
    Last update posted :
    02/20/2025
    Initiation :
    02/28/2019
    Primary completion :
    02/02/2023
    Completion :
    12/22/2024
    CD33
    |
    CD33 expression
    |
    etoposide IV • Mylotarg (gemtuzumab ozogamicin) • mitoxantrone
    CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia (NCT04375631)
    Phase 1
    Fred Hutchinson Cancer Center
    Recruiting
    Last update posted :
    02/20/2025
    Initiation :
    12/03/2020
    Primary completion :
    02/28/2027
    Completion :
    03/17/2027
    HLA-DRB1 • HLA-DQB1 • HLA-B • HLA-C
    |
    cytarabine • cyclophosphamide • idarubicin hydrochloride • mitoxantrone • cladribine • fludarabine IV • cyclosporin A microemulsion • Neupogen (filgrastim) • Starasid (cytarabine ocfosfate) • cyclophosphamide intravenous
    A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations (NCT04293562)
    Phase 3
    Children's Oncology Group
    Active, not recruiting
    Last update posted :
    02/13/2025
    Initiation :
    07/21/2020
    Primary completion :
    09/30/2027
    Completion :
    09/30/2027
    FLT3
    |
    Xospata (gilteritinib) • etoposide IV • methotrexate • Mylotarg (gemtuzumab ozogamicin) • Vyxeos (cytarabine/daunorubicin liposomal formulation) • mitoxantrone • Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) • Erwinase (erwinia asparaginase) • Kidrolase (L-asparaginase) • Leunase (L-asparaginase) • Spectrila (asparaginase Escherichia coli) • Starasid (cytarabine ocfosfate) • dexrazoxane
    Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) (NCI-MATCH) (NCT02465060)
    Phase 2
    National Cancer Institute (NCI)
    Active, not recruiting
    Last update posted :
    02/06/2025
    Initiation :
    08/17/2015
    Primary completion :
    12/31/2025
    Completion :
    12/31/2025
    MSI • CD4
    |
    PD-L1 expression
    |
    Keytruda (pembrolizumab) • Opdivo (nivolumab) • Avastin (bevacizumab) • Herceptin (trastuzumab) • Lynparza (olaparib) • Mekinist (trametinib) • cisplatin • Xalkori (crizotinib) • Tagrisso (osimertinib) • Tecentriq (atezolizumab) • Gilotrif (afatinib) • Yervoy (ipilimumab) • Ibrance (palbociclib) • dasatinib • Tafinlar (dabrafenib) • carboplatin • Imfinzi (durvalumab) • Vitrakvi (larotrectinib) • Imbruvica (ibrutinib) • gemcitabine • paclitaxel • Rituxan (rituximab) • docetaxel • 5-fluorouracil • sunitinib • everolimus • Vectibix (panitumumab) • temozolomide • Koselugo (selumetinib) • Perjeta (pertuzumab) • cytarabine • Kadcyla (ado-trastuzumab emtansine) • bortezomib • doxorubicin hydrochloride • Talzenna (talazoparib) • capecitabine • Piqray (alpelisib) • Xtandi (enzalutamide) • azacitidine • Cabometyx (cabozantinib tablet) • Balversa (erdafitinib) • Gazyva (obinutuzumab) • Mektovi (binimetinib) • albumin-bound paclitaxel • cyclophosphamide • Imjudo (tremelimumab-actl) • Cyramza (ramucirumab) • pemetrexed • fulvestrant • oxaliplatin • adavosertib (AZD1775) • etoposide IV • irinotecan • Halaven (eribulin mesylate) • Xpovio (selinexor) • Conmana (icotinib) • Pemazyre (pemigatinib) • Truqap (capivasertib) • methotrexate • Zarnestra (tipifarnib) • Aliqopa (copanlisib) • fexagratinib (ABSK091) • Ninlaro (ixazomib) • pegylated liposomal doxorubicin • epirubicin • sapanisertib (CB-228) • ipatasertib (RG7440) • Caprelsa (vandetanib) • vincristine • vinorelbine tartrate • Cometriq (cabozantinib capsule) • Tabrecta (capmatinib) • spartalizumab (PDR001) • taselisib (GDC-0032) • daunorubicin • omipalisib (GSK2126458) • ulixertinib (BVD-523) • mitoxantrone • Erivedge (vismodegib) • carmustine • bicalutamide • leucovorin calcium • bendamustine • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Zepzelca (lurbinectedin) • mitomycin • Jingzhuda (entinostat) • Recentin (cediranib) • Trazimera (trastuzumab-qyyp) • melphalan • GSK2636771 • Zirabev (bevacizumab-bvzr) • defactinib (VS-6063) • goserelin acetate • Zynyz (retifanlimab-dlwr) • fludarabine IV • Ostarine (enobosarm) • avadomide (CC-122) • vistusertib (AZD2014) • Myocet (non-pegylated liposomal doxorubicin) • mesna • vinblastine • Xofigo (radium Ra-223 dichloride) • lorvotuzumab mertansine (IMGN901) • Ampligen (rintatolimod) • E6201 • Fujovee (abivertinib) • Provenge (sipuleucel-T) • TQB2440 (pertuzumab biosimilar) • relatlimab (BMS-986016) • ABP 206 (nivolumab biosimilar) • Airuituo (bevacizumab biosimilar) • BCD-178 (pertuzumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • CC-90002 • EG1206A (pertuzumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • ImmuniCell (autologous γδ T lymphocytes) • Leukine (sargramostim) • Vasforda (bevacizumab biosimilar) • celecoxib oral • cyclophosphamide intravenous • dexamethasone injection • ieramilimab (LAG525) • levoleucovorin calcium • methotrexate IV • sapitinib (AZD8931)
    Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia (AAML1031) (NCT01371981)
    Phase 3
    National Cancer Institute (NCI)
    Active, not recruiting
    Last update posted :
    02/04/2025
    Initiation :
    06/20/2011
    Primary completion :
    03/31/2019
    Completion :
    09/30/2027
    FLT3
    |
    FLT3-ITD mutation
    |
    sorafenib • cytarabine • bortezomib • etoposide IV • daunorubicin • mitoxantrone • Kidrolase (L-asparaginase) • Leunase (L-asparaginase) • Spectrila (asparaginase Escherichia coli) • Starasid (cytarabine ocfosfate)
    TINI 2: Total Therapy for Infants with Acute Lymphoblastic Leukemia II (NCT05848687)
    Phase 1/2
    Tanja Andrea Gruber
    Recruiting
    Last update posted :
    01/31/2025
    Initiation :
    11/03/2023
    Primary completion :
    12/01/2028
    Completion :
    12/01/2033
    KMT2A
    |
    CD19 positive
    |
    bortezomib • Blincyto (blinatumomab) • Zolinza (vorinostat) • dexamethasone • mitoxantrone • ziftomenib (KO-539) • mercaptopurine
    Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation (AG120-221-C-001) (NCT02632708)
    Phase 1
    Institut de Recherches Internationales Servier
    Active, not recruiting
    Last update posted :
    07/25/2024
    Initiation :
    12/31/2015
    Primary completion :
    12/13/2018
    Completion :
    07/01/2024
    IDH1 • IDH2 • UGT1A1
    |
    IDH2 mutation • UGT1A1*1*1 • Chr t(15;17) • UGT1A1 mutation
    |
    cytarabine • etoposide IV • Tibsovo (ivosidenib) • daunorubicin • Idhifa (enasidenib) • idarubicin hydrochloride • mitoxantrone
    Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia (NCT03983824)
    Phase 1
    National Cancer Institute (NCI)
    Suspended
    Last update posted :
    06/04/2024
    Initiation :
    05/05/2020
    Primary completion :
    06/30/2025
    Completion :
    06/30/2025
    RARA • PML • CD4
    |
    cytarabine • etoposide IV • mitoxantrone • peposertib (M3814) • Starasid (cytarabine ocfosfate)
    A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FLT3 Mutation (COMMODORE) (NCT03182244)
    Phase 3
    Astellas Pharma Inc
    Active, not recruiting
    Last update posted :
    05/24/2024
    Initiation :
    01/15/2018
    Primary completion :
    12/25/2023
    Completion :
    03/31/2026
    FLT3
    |
    FLT3-ITD mutation • FLT3 mutation • FLT3 D835 • FLT3 I836
    |
    cytarabine • Xospata (gilteritinib) • etoposide IV • mitoxantrone • fludarabine IV
    A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation (ADMIRAL) (NCT02421939)
    Phase 3
    Astellas Pharma Global Development, Inc.
    Active, not recruiting
    Last update posted :
    05/23/2024
    Initiation :
    10/20/2015
    Primary completion :
    09/17/2018
    Completion :
    07/31/2024
    FLT3
    |
    FLT3-ITD mutation • FLT3 mutation • FLT3 D835 • FLT3 I836
    |
    cytarabine • Xospata (gilteritinib) • azacitidine • etoposide IV • idarubicin hydrochloride • mitoxantrone • fludarabine IV
    A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML (NCT03591510)
    Phase 2
    Novartis Pharmaceuticals
    Recruiting
    Last update posted :
    04/05/2024
    Initiation :
    03/13/2019
    Primary completion :
    08/18/2025
    Completion :
    02/15/2029
    FLT3
    |
    FLT3 mutation
    |
    cytarabine • etoposide IV • midostaurin • daunorubicin • idarubicin hydrochloride • mitoxantrone • fludarabine IV
    Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patients (NCT02400281)
    Phase 1/2
    Arog Pharmaceuticals, Inc.
    Completed
    Last update posted :
    03/20/2024
    Initiation :
    09/01/2015
    Primary completion :
    07/15/2020
    Completion :
    07/15/2020
    FLT3
    |
    FLT3 mutation
    |
    cytarabine • azacitidine • etoposide IV • crenolanib (ARO-002) • idarubicin hydrochloride • mitoxantrone • fludarabine IV
    Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX) (NCT04330820)
    Phase 1/2
    Technische Universität Dresden
    Active, not recruiting
    Last update posted :
    02/28/2024
    Initiation :
    04/06/2020
    Primary completion :
    10/11/2023
    Completion :
    08/01/2025
    TP53 • JAK2 • RUNX1 • PDGFRB • WT1
    |
    Venclexta (venetoclax) • cytarabine • mitoxantrone
    Impact of Remission Induction Chemotherapy Prior to Allogeneic SCT in Relapsed and Poor-response Patients With AML (ETAL3-ASAP) (NCT02461537)
    Phase 3
    DKMS gemeinnützige GmbH
    Completed
    Last update posted :
    01/19/2024
    Initiation :
    09/17/2015
    Primary completion :
    04/05/2022
    Completion :
    01/12/2024
    HLA-DRB1
    |
    cytarabine • mitoxantrone
    Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome (NCT02521493)
    Phase 3
    Children's Oncology Group
    Active, not recruiting
    Last update posted :
    11/24/2023
    Initiation :
    12/23/2015
    Primary completion :
    06/30/2024
    Completion :
    06/30/2024
    GATA1
    |
    cytarabine • etoposide IV • daunorubicin • mitoxantrone • mercaptopurine delayed release (DR6MP) • mercaptopurine • Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) • thioguanine • Erwinase (erwinia asparaginase) • Kidrolase (L-asparaginase) • Leunase (L-asparaginase) • Spectrila (asparaginase Escherichia coli) • Starasid (cytarabine ocfosfate)
    Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia (NCT02339740)
    Phase 3
    Children's Oncology Group
    Active, not recruiting
    Last update posted :
    11/22/2023
    Initiation :
    07/21/2015
    Primary completion :
    10/31/2020
    Completion :
    09/22/2024
    FLT3 • RARA • PML
    |
    FLT3 mutation • FLT3 wild-type
    |
    cytarabine • idarubicin hydrochloride • mitoxantrone • Vesanoid (tretinoin) • arsenic trioxide • Hemady (dexamethasone tablets) • Starasid (cytarabine ocfosfate)
    Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia (TUD-APOLLO-064) (NCT02688140)
    Phase 3
    Technische Universität Dresden
    Active, not recruiting
    Last update posted :
    11/02/2023
    Initiation :
    06/01/2016
    Primary completion :
    01/01/2025
    Completion :
    01/01/2025
    PML
    |
    PML-RARA fusion • Chr t(15;17) • Chr t(15;17)/PML-RARA fusion
    |
    cytarabine • idarubicin hydrochloride • mitoxantrone • arsenic trioxide • mercaptopurine
    Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy (NCT00005847)
    Phase 2
    Eastern Cooperative Oncology Group
    Completed
    Last update posted :
    06/22/2023
    Initiation :
    04/05/2001
    Primary completion :
    07/01/2004
    BCL2
    |
    paclitaxel • vinorelbine tartrate • mitoxantrone • Emcyt (estramustine)
    GM-CLAG in Relapsed/Refractory FLT3-mutated AML (NCT05330377)
    Phase 1
    Ayman H Qasrawi
    Withdrawn
    Last update posted :
    04/25/2023
    Initiation :
    03/01/2023
    Primary completion :
    05/30/2027
    Completion :
    05/30/2032
    FLT3
    |
    FLT3-ITD mutation • FLT3-TKD mutation
    |
    cytarabine • Xospata (gilteritinib) • mitoxantrone • cladribine • Neupogen (filgrastim)
    Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage (NCT03926624)
    Phase 3
    Delta-Fly Pharma, Inc.
    Recruiting
    Last update posted :
    10/20/2022
    Initiation :
    11/22/2019
    Primary completion :
    12/01/2022
    Completion :
    12/01/2022
    IDH1 • BCL2
    |
    Venclexta (venetoclax) • cytarabine • azacitidine • etoposide IV • decitabine • idarubicin hydrochloride • mitoxantrone • cladribine • fludarabine IV • radgocitabine (DFP-10917)
    Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma (NCT01700946)
    Phase 2
    St. Jude Children's Research Hospital
    Completed
    Last update posted :
    09/28/2022
    Initiation :
    04/15/2013
    Primary completion :
    07/24/2021
    Completion :
    07/24/2021
    CD20
    |
    CD20 expression
    |
    Rituxan (rituximab) • cytarabine • cyclophosphamide • etoposide IV • methotrexate • vincristine • clofarabine • mitoxantrone • Oncaspar liquid (pegaspargase) • Vumon (teniposide) • mercaptopurine • vinblastine • Proleukin (aldesleukin) • cyclophosphamide intravenous
    The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid Leukemia (NCT03173612)
    Phase N/A
    Institute of Hematology & Blood Diseases Hospital
    Recruiting
    Last update posted :
    08/03/2022
    Initiation :
    08/01/2016
    Primary completion :
    12/01/2024
    Completion :
    12/01/2024
    GATA1
    |
    dasatinib • cytarabine • etoposide IV • idarubicin hydrochloride • mitoxantrone • aclarubicin
    Therapy for Patients With Untreated Age-Adjusted International Prognostic Index Low-Intermediate Risk, High-Intermediate Risk, or High Risk Diffuse Large B Cell Lymphoma (NCT00712582)
    Phase 2
    Memorial Sloan Kettering Cancer Center
    Completed
    Last update posted :
    06/21/2022
    Initiation :
    07/01/2008
    Primary completion :
    03/12/2021
    Completion :
    03/12/2021
    CD20
    |
    CD20 expression
    |
    carboplatin • Rituxan (rituximab) • cyclophosphamide • ifosfamide • etoposide IV • mitoxantrone • carmustine
    A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia (NCT02200978)
    Phase 4
    South China Children's Leukemia Group
    Completed
    Last update posted :
    05/10/2022
    Initiation :
    09/01/2011
    Primary completion :
    10/01/2021
    Completion :
    10/01/2021
    PML
    |
    RARA positive
    |
    cytarabine • methotrexate • mitoxantrone • arsenic trioxide • mercaptopurine
    Rituximab, Fludarabine, Mitoxantrone, Dexamethasone (R-FND) Plus Zevalin for High-Risk Follicular Lymphoma (NCT00290511)
    Phase 2
    M.D. Anderson Cancer Center
    Completed
    Last update posted :
    04/22/2022
    Initiation :
    06/29/2004
    Primary completion :
    02/12/2021
    Completion :
    02/12/2021
    BCL2
    |
    LDH elevation
    |
    Rituxan (rituximab) • mitoxantrone • fludarabine IV • Zevalin (ibritumomab tiuxetan)
    Combination Chemotherapy and Rituximab With Pegfilgrastim Followed by Rituximab, in Large B-Cell Non-Hodgkin's Lymphoma (NCT00193479)
    Phase 2
    SCRI Development Innovations, LLC
    Completed
    Last update posted :
    03/03/2022
    Initiation :
    04/01/2003
    Primary completion :
    07/01/2008
    Completion :
    02/01/2010
    CD20
    |
    CD20 positive
    |
    Rituxan (rituximab) • cyclophosphamide • vincristine • prednisone • mitoxantrone • Neulasta (pegfilgrastim) • cyclophosphamide intravenous
    Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms (NCT02756572)
    Phase 2
    University of Washington
    Completed
    Last update posted :
    11/08/2021
    Initiation :
    09/22/2016
    Primary completion :
    03/01/2020
    Completion :
    07/01/2020
    HLA-B
    |
    cytarabine • sirolimus • mitoxantrone • cladribine • fludarabine IV • cyclosporin A microemulsion • Neupogen (filgrastim) • Starasid (cytarabine ocfosfate) • captisol-enabled melphalan
    Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML (NCT03250338)
    Phase 3
    Arog Pharmaceuticals, Inc.
    Recruiting
    Last update posted :
    04/30/2021
    Initiation :
    06/05/2018
    Primary completion :
    10/01/2024
    Completion :
    10/01/2024
    FLT3
    |
    FLT3-ITD mutation • FLT3 D835
    |
    cytarabine • crenolanib (ARO-002) • idarubicin hydrochloride • mitoxantrone
    Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia (AAML0531) (NCT00372593)
    Phase 3
    Children's Oncology Group
    Completed
    Last update posted :
    03/24/2021
    Initiation :
    08/01/2006
    Primary completion :
    08/01/2013
    Completion :
    09/30/2020
    HLA-DRB1 • HLA-B • HLA-C
    |
    cytarabine • etoposide IV • Mylotarg (gemtuzumab ozogamicin) • daunorubicin • mitoxantrone • Kidrolase (L-asparaginase) • Leunase (L-asparaginase)
    Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia (NCT01839240)
    Phase 1
    University of Chicago
    Completed
    Last update posted :
    05/15/2020
    Initiation :
    06/06/2012
    Primary completion :
    08/16/2019
    Completion :
    08/16/2019
    DCK
    |
    TOP2A expression
    |
    cytarabine • azacitidine • mitoxantrone
    Brentuximab Vedotin + Re-induction Chemotherapy for AML (NCT01830777)
    Phase 1
    Massachusetts General Hospital
    Completed
    Last update posted :
    04/14/2020
    Initiation :
    05/01/2013
    Primary completion :
    04/01/2018
    Completion :
    05/01/2019
    TNFRSF8
    |
    TNFRSF8 expression
    |
    cytarabine • etoposide IV • Adcetris (brentuximab vedotin) • mitoxantrone
    A Study of Olaratumab (IMC-3G3) in Prostate Cancer (NCT01204710)
    Phase 2
    Eli Lilly and Company
    Completed
    Last update posted :
    09/20/2019
    Initiation :
    10/01/2010
    Primary completion :
    09/01/2012
    Completion :
    10/01/2013
    PDGFRA
    |
    PDGFRA expression
    |
    docetaxel • prednisone • mitoxantrone • Lartruvo (olaratumab)
    Fludarabine, Mitoxantrone and Rituximab in Relapsed or Primary Failing Advanced Follicular Non-Hodgkin's Lymphoma (NCT00169208)
    Phase 2
    Lymphoma Study Association
    Completed
    Last update posted :
    08/28/2019
    Initiation :
    04/01/2001
    Primary completion :
    12/01/2006
    Completion :
    12/01/2006
    BCL2 • CD20
    |
    CD20 positive
    |
    Rituxan (rituximab) • mitoxantrone • fludarabine IV
    Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia (Interfant06) (NCT00550992)
    Phase N/A
    Dutch Childhood Oncology Group
    Unknown status
    Last update posted :
    07/30/2019
    Initiation :
    01/01/2006
    Primary completion :
    12/01/2020
    KMT2A • CD34
    |
    MLL rearrangement • MLL rearrangement • CD34 positive
    |
    cytarabine • cyclophosphamide • etoposide IV • vincristine • prednisone • daunorubicin • mitoxantrone • leucovorin calcium • melphalan • Oncaspar liquid (pegaspargase) • mercaptopurine • busulfan • thioguanine • cyclosporine • prednisolone
    Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia (LAL0904) (NCT00458848)
    Phase 2
    Gruppo Italiano Malattie EMatologiche dell'Adulto
    Completed
    Last update posted :
    02/15/2019
    Initiation :
    10/01/2004
    Primary completion :
    03/01/2014
    Completion :
    03/01/2014
    MPO
    |
    imatinib • etoposide IV • vincristine • prednisone • daunorubicin • idarubicin hydrochloride • mitoxantrone • mercaptopurine
    A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia (INO-VATE) (NCT01564784)
    Phase 3
    Pfizer
    Completed
    Last update posted :
    01/09/2019
    Initiation :
    08/02/2012
    Primary completion :
    03/08/2016
    Completion :
    01/04/2017
    CD22 • IL3RA • ANPEP
    |
    CD22 expression
    |
    cytarabine • Besponsa (inotuzumab ozogamicin) • mitoxantrone • fludarabine IV
    Ixazomib, Mitoxantrone Hydrochloride, Etoposide, and Intermediate-Dose Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia (NCT02070458)
    Phase 1
    Case Comprehensive Cancer Center
    Completed
    Last update posted :
    12/13/2018
    Initiation :
    10/08/2014
    Primary completion :
    03/17/2017
    Completion :
    08/15/2017
    CD74
    |
    cytarabine • etoposide IV • Ninlaro (ixazomib) • mitoxantrone