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    DRUG:

    methylprednisolone sodium succinate

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    Company:
    Generic mfg.
    Drug class:
    GCR agonist
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    Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies (NCT04599634)
    Phase 1
    National Cancer Institute (NCI)
    Completed
    Last update posted :
    02/04/2025
    Initiation :
    12/16/2021
    Primary completion :
    03/29/2024
    Completion :
    06/20/2024
    TP53 • BCL2
    |
    TP53 mutation • CD20 positive
    |
    Venclexta (venetoclax) • Gazyva (obinutuzumab) • magrolimab (ONO-7913) • methylprednisolone acetate • methylprednisolone sodium succinate
    Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia (NCT03913559)
    Phase 2
    St. Jude Children's Research Hospital
    Recruiting
    Last update posted :
    04/19/2024
    Initiation :
    05/14/2019
    Primary completion :
    12/01/2024
    Completion :
    01/01/2025
    CD22
    |
    CD22 expression
    |
    cytarabine • methotrexate • Besponsa (inotuzumab ozogamicin) • methylprednisolone sodium succinate
    Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma (NCT04479267)
    Phase 2
    Barbara Ann Karmanos Cancer Institute
    Recruiting
    Last update posted :
    03/20/2024
    Initiation :
    08/21/2020
    Primary completion :
    11/15/2025
    Completion :
    11/15/2026
    MYC • BCL2 • BCL6
    |
    MYC overexpression • MYC expression • BCL6 rearrangement • BCL2 rearrangement
    |
    Rituxan (rituximab) • doxorubicin hydrochloride • cyclophosphamide • prednisone • Truxima (rituximab-abbs) • Polivy (polatuzumab vedotin-piiq) • Riabni (rituximab-arrx) • cyclophosphamide intravenous • methylprednisolone sodium succinate • prednisolone
    Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis (NCT04305145)
    Phase 2
    Massachusetts General Hospital
    Recruiting
    Last update posted :
    03/15/2024
    Initiation :
    08/31/2020
    Primary completion :
    06/30/2030
    Completion :
    06/30/2030
    PD-L1 • PD-1
    |
    Yervoy (ipilimumab) • methylprednisolone sodium succinate
    Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma (ZUMA-7) (NCT03391466)
    Phase 3
    Kite, A Gilead Company
    Active, not recruiting
    Last update posted :
    03/07/2024
    Initiation :
    01/25/2018
    Primary completion :
    03/18/2021
    Completion :
    10/01/2024
    BCL2 • BCL6
    |
    BCL6 rearrangement • BCL2 rearrangement • CD20 negative
    |
    carboplatin • cytarabine • cyclophosphamide • oxaliplatin • Yescarta (axicabtagene ciloleucel) • fludarabine IV • cyclophosphamide intravenous • methylprednisolone sodium succinate
    BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant (BRESELIBET) (NCT04378647)
    Phase 2
    Grupo Español de Linfomas y Transplante Autólog...
    Recruiting
    Last update posted :
    02/26/2024
    Initiation :
    06/01/2020
    Primary completion :
    08/30/2026
    Completion :
    08/30/2026
    TNFRSF8
    |
    cytarabine • Adcetris (brentuximab vedotin) • methylprednisolone sodium succinate
    Tandem Stem Cell Transplantation for Non-Hodgkin's Lymphoma (NCT00882895)
    Phase 2
    Washington University School of Medicine
    Active, not recruiting
    Last update posted :
    01/23/2024
    Initiation :
    05/05/2009
    Primary completion :
    06/01/2028
    Completion :
    06/01/2028
    CD34
    |
    melphalan • methylprednisolone sodium succinate
    Allo HSCT Using RIC for Hematological Diseases (NCT02661035)
    Phase 2
    Masonic Cancer Center, University of Minnesota
    Completed
    Last update posted :
    09/21/2023
    Initiation :
    03/09/2017
    Primary completion :
    04/17/2023
    Completion :
    05/29/2023
    FLT3 • KMT2A • IKZF1 • HLA-DRB1 • HLA-B • HLA-C
    |
    MLL rearrangement • MLL rearrangement
    |
    cyclophosphamide • fludarabine IV • cyclophosphamide intravenous • methylprednisolone sodium succinate
    Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related Hepatitis (I-HEP) (NCT04810156)
    Phase 2
    Inge Marie Svane
    Recruiting
    Last update posted :
    12/14/2022
    Initiation :
    04/07/2021
    Primary completion :
    04/07/2025
    Completion :
    11/07/2025
    PD-L1
    |
    prednisone • methylprednisolone sodium succinate • prednisolone
    Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor (NCT02500550)
    Phase 2
    Kiadis Pharma
    Completed
    Last update posted :
    05/18/2021
    Initiation :
    10/09/2015
    Primary completion :
    07/01/2018
    Completion :
    12/17/2018
    HLA-B
    |
    Rhitol (allodepleted T-cell immunotherapeutics) • methylprednisolone sodium succinate
    Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies (NCT00068523)
    Phase N/A
    Case Comprehensive Cancer Center
    Completed
    Last update posted :
    07/27/2020
    Initiation :
    06/01/2003
    Primary completion :
    03/01/2004
    CCND1 • HLA-B
    |
    cyclophosphamide • fludarabine IV • cyclosporine • cyclophosphamide intravenous • methylprednisolone oral • methylprednisolone sodium succinate
    Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia (NCT00553202)
    Phase 2
    Children's Oncology Group
    Completed
    Last update posted :
    04/16/2020
    Initiation :
    01/01/2008
    Primary completion :
    06/01/2016
    Completion :
    03/31/2020
    FLT3 • CEBPA
    |
    FLT3-ITD mutation
    |
    cyclophosphamide • busulfan • cyclosporin A microemulsion • cyclophosphamide intravenous • methotrexate IV • methylprednisolone sodium succinate
    Allogeneic Transplantation From Related Haploidentical Donors (NCT00185692)
    Phase 2
    Stanford University
    Completed
    Last update posted :
    12/04/2019
    Initiation :
    08/01/2000
    Primary completion :
    12/01/2010
    Completion :
    12/01/2010
    CD34
    |
    cyclosporine • methylprednisolone acetate • methylprednisolone sodium succinate
    Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies (NCT01093586)
    Phase 2
    Case Comprehensive Cancer Center
    Completed
    Last update posted :
    01/23/2019
    Initiation :
    09/01/2007
    Primary completion :
    12/01/2015
    Completion :
    12/01/2015
    KMT2A • HLA-B
    |
    MLL rearrangement
    |
    cyclophosphamide • busulfan • cyclosporin A microemulsion • cyclophosphamide intravenous • methylprednisolone acetate • methylprednisolone sodium succinate
    Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (AALL1131) (NCT01406756)
    Phase 3
    Children's Oncology Group
    Recruiting
    Last update posted :
    12/13/2017
    Initiation :
    02/01/2012
    Primary completion :
    08/01/2021
    ABL1 • BCR • RUNX1 • KMT2A • ETV6
    |
    MLL rearrangement • MLL rearrangement
    |
    cytarabine • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • methotrexate • vincristine • prednisone • dexamethasone • clofarabine • leucovorin calcium • Oncaspar liquid (pegaspargase) • mercaptopurine delayed release (DR6MP) • mercaptopurine • thioguanine • Starasid (cytarabine ocfosfate) • cyclophosphamide intravenous • dexamethasone injection • methylprednisolone sodium succinate
    Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG (NCT00899847)
    Phase 2
    Stanford University
    Completed
    Last update posted :
    10/20/2017
    Initiation :
    05/01/2009
    Primary completion :
    04/01/2014
    Completion :
    12/01/2014
    HLA-DRB1 • HLA-B • HLA-C
    |
    cyclophosphamide • melphalan • cyclosporin A microemulsion • Neupogen (filgrastim) • cyclophosphamide intravenous • methylprednisolone sodium succinate