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    DRUG:

    Matulane (procarbazine hydrochloride)

    Company:
    Leadiant Biosci
    Drug class:
    Alkylating agent
    Related drugs:
    Apply
    Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous System (FIORELLA) (NCT03495960)
    Phase 2
    International Extranodal Lymphoma Study Group (...
    Completed
    Last update posted :
    01/30/2025
    Initiation :
    06/15/2019
    Primary completion :
    12/12/2024
    Completion :
    12/12/2024
    CD20
    |
    Rituxan (rituximab) • lenalidomide • temozolomide • Matulane (procarbazine hydrochloride)
    Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma (NCT00887146)
    Phase 3
    Alliance for Clinical Trials in Oncology
    Recruiting
    Last update posted :
    05/23/2024
    Initiation :
    09/01/2009
    Primary completion :
    10/01/2025
    Completion :
    10/01/2025
    IDH1 • IDH2
    |
    temozolomide • vincristine • Matulane (procarbazine hydrochloride)
    Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma (NCT00574496)
    Phase 2
    Memorial Sloan Kettering Cancer Center
    Completed
    Last update posted :
    09/27/2023
    Initiation :
    11/13/2007
    Primary completion :
    08/02/2022
    Completion :
    08/02/2022
    CD20 • HLA-DRB1 • HLA-B
    |
    gemcitabine • cyclophosphamide • ifosfamide • vincristine • vinorelbine tartrate • prednisone • melphalan • fludarabine IV • Matulane (procarbazine hydrochloride) • cyclosporine • Mustargen (mechlorethamine)
    Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma (NCT01775475)
    Phase 2
    AIDS Malignancy Consortium
    Completed
    Last update posted :
    10/10/2022
    Initiation :
    09/15/2016
    Primary completion :
    04/01/2021
    Completion :
    07/15/2021
    CD4
    |
    doxorubicin hydrochloride • cyclophosphamide • etoposide IV • vincristine • prednisone • lomustine • Matulane (procarbazine hydrochloride) • cyclophosphamide intravenous
    S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma (NCT00822120)
    Phase 2
    Southwest Oncology Group
    Completed
    Last update posted :
    08/18/2022
    Initiation :
    07/01/2009
    Primary completion :
    04/30/2016
    Completion :
    06/30/2022
    CD4
    |
    doxorubicin hydrochloride • cyclophosphamide • etoposide IV • vincristine • prednisone • dacarbazine • Matulane (procarbazine hydrochloride) • bleomycin • vinblastine • Neupogen (filgrastim) • cyclophosphamide intravenous
    Brentuximab Vedotin as Consolidation Treatment in Patients With Stage I/II HL and PET Positivity After 2 Cycles of ABVD (BRAPP2) (NCT02298283)
    Phase 2
    The Lymphoma Academic Research Organisation
    Completed
    Last update posted :
    07/26/2021
    Initiation :
    04/01/2015
    Primary completion :
    07/09/2020
    Completion :
    07/09/2020
    TNFRSF8
    |
    doxorubicin hydrochloride • cyclophosphamide • etoposide IV • Adcetris (brentuximab vedotin) • vincristine • prednisone • Matulane (procarbazine hydrochloride) • bleomycin • cyclophosphamide intravenous
    Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma (NCT01132807)
    Phase 2
    Alliance for Clinical Trials in Oncology
    Completed
    Last update posted :
    06/14/2021
    Initiation :
    05/01/2010
    Primary completion :
    02/01/2016
    Completion :
    01/01/2018
    CD4
    |
    doxorubicin hydrochloride • cyclophosphamide • etoposide IV • prednisone • dacarbazine • Matulane (procarbazine hydrochloride) • bleomycin • vinblastine • cyclophosphamide intravenous
    Phase II Study of RT-PEPC in Relapsed Mantle Cell Lymphoma (NCT00151281)
    Phase 2
    Weill Medical College of Cornell University
    Completed
    Last update posted :
    06/28/2018
    Initiation :
    11/01/2004
    Primary completion :
    12/01/2009
    Completion :
    04/07/2011
    CD20 • CCND1 • CD5 • MME • FCER2
    |
    Rituxan (rituximab) • cyclophosphamide • etoposide IV • prednisone • thalidomide • Matulane (procarbazine hydrochloride)