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    Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies (LONCA) (NCT05270057)
    Phase 1
    Medical College of Wisconsin
    Recruiting
    Last update posted :
    06/04/2024
    Initiation :
    01/26/2023
    Primary completion :
    05/01/2026
    Completion :
    05/01/2026
    BCL2 • BCL6
    |
    MYC rearrangement • BCL6 rearrangement
    |
    Rituxan (rituximab) • cyclophosphamide • etoposide IV • pegylated liposomal doxorubicin • vincristine • prednisone • Zynlonta (loncastuximab tesirine-lpyl) • Marqibo (vincristine liposomal)
    OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients With CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine (NCT01478542)
    Phase 3
    Universität des Saarlandes
    Completed
    Last update posted :
    04/26/2024
    Initiation :
    11/01/2011
    Primary completion :
    01/18/2024
    Completion :
    01/18/2024
    ALK • CD20
    |
    ALK positive
    |
    Rituxan (rituximab) • cyclophosphamide • Marqibo (vincristine liposomal)
    Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia (NCI-2018-01198) (NCT03136146)
    Phase 2
    M.D. Anderson Cancer Center
    Recruiting
    Last update posted :
    03/29/2024
    Initiation :
    08/09/2017
    Primary completion :
    08/01/2025
    Completion :
    08/01/2026
    BCL2
    |
    Rituxan (rituximab) • bortezomib • cyclophosphamide • etoposide IV • clofarabine • Arzerra (ofatumumab) • Truxima (rituximab-abbs) • Marqibo (vincristine liposomal) • Riabni (rituximab-arrx) • Delito (rituximab biosimilar) • Hemady (dexamethasone tablets) • Neulasta (pegfilgrastim) • Fulphila (pegfilgrastim-jmdb) • GB241 (rituximab biosimilar) • Neupogen (filgrastim) • Novex (rituximab biosimilar) • cyclophosphamide intravenous
    Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia (ECOG-ACRIN EA9152) (NCT03504644)
    Phase 1/2
    ECOG-ACRIN Cancer Research Group
    Recruiting
    Last update posted :
    06/23/2023
    Initiation :
    08/13/2018
    Primary completion :
    12/31/2028
    Completion :
    12/31/2028
    BCL2
    |
    BCL2 expression
    |
    Venclexta (venetoclax) • Marqibo (vincristine liposomal)
    Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma (NCT00567567)
    Phase 3
    Children's Oncology Group
    Completed
    Last update posted :
    04/28/2022
    Initiation :
    11/05/2007
    Primary completion :
    02/27/2015
    Completion :
    03/31/2022
    CD8 • MYCN • UGT1A1 • CD4
    |
    MYCN amplification • UGT1A1*1*1
    |
    cisplatin • carboplatin • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • topotecan • melphalan • Marqibo (vincristine liposomal) • thiotepa • Neupogen (filgrastim) • cyclophosphamide intravenous
    Inotuzumab Ozogamicin and Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (NCT03851081)
    Phase 1b/2
    Roswell Park Cancer Institute
    Withdrawn
    Last update posted :
    01/28/2022
    Initiation :
    01/21/2021
    Primary completion :
    01/21/2023
    Completion :
    01/21/2024
    CD22
    |
    CD22 positive
    |
    Besponsa (inotuzumab ozogamicin) • Marqibo (vincristine liposomal)
    Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas (NCT01445535)
    Phase 1
    National Cancer Institute (NCI)
    Completed
    Last update posted :
    11/03/2021
    Initiation :
    01/13/2009
    Primary completion :
    04/01/2011
    Completion :
    10/22/2020
    ALK • CD2
    |
    ALK positive
    |
    Rituxan (rituximab) • cyclophosphamide • etoposide IV • pegylated liposomal doxorubicin • vincristine • prednisone • Marqibo (vincristine liposomal) • cyclophosphamide intravenous • doxorubicin liposomal
    Phase 1/2 Study of VSLI Plus Rituximab in Patients With Relapsed and/or Refractory NHL (NCT01851551)
    Phase 1/2
    Acrotech Biopharma LLC
    Completed
    Last update posted :
    01/03/2020
    Initiation :
    09/01/2001
    Primary completion :
    04/01/2004
    Completion :
    04/01/2005
    CD20
    |
    CD20 expression
    |
    Rituxan (rituximab) • Marqibo (vincristine liposomal)
    Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL) (NCT00098839)
    Phase 2
    Children's Oncology Group
    Completed
    Last update posted :
    12/12/2017
    Initiation :
    02/01/2005
    Primary completion :
    04/01/2011
    Completion :
    04/01/2011
    CD22
    |
    CD22 expression
    |
    cytarabine • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • prednisone • leucovorin calcium • Oncaspar liquid (pegaspargase) • Marqibo (vincristine liposomal) • Epratucyn (epratuzumab) • Neupogen (filgrastim) • cyclophosphamide intravenous • dexrazoxane