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    DRUG:

    rupitasertib (DIACC3010)

    i
    Company:
    EMD Serono, Evexta Bio
    Drug class:
    AKT inhibitor, p70S6K inhibitor, AKT1 inhibitor, AKT3 inhibitor
    Related drugs:
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    First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies (EMR100018-001) (NCT01971515)
    Phase 1
    EMD Serono
    Completed
    Last update posted :
    09/19/2018
    Initiation :
    12/13/2013
    Primary completion :
    08/09/2018
    Completion :
    08/09/2018
    HER-2 • ER • PIK3CA • PGR • PTEN • AKT1 • mTOR • TSC2 • TSC1 • AKT2
    |
    HR positive • HER-2 negative • PGR positive
    |
    Herceptin (trastuzumab) • tamoxifen • rupitasertib (DIACC3010)