^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    DRUG:

    KRAS peptide vaccine

    i
    Associations
    News

    Trials

    Company:
    Sidney Kimmel Comprehensive Cancer Center
    Drug class:
    Immunostimulant, KRAS inhibitor
    Related drugs:
    Associations
    News

    Trials

    Apply
    Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer (IRB00210915) (NCT04117087)
    Phase 1
    Sidney Kimmel Comprehensive Cancer Center at Jo...
    Recruiting
    Last update posted :
    02/03/2025
    Initiation :
    05/28/2020
    Primary completion :
    08/08/2025
    Completion :
    08/08/2025
    KRAS • CD8 • CD4
    |
    KRAS mutation
    |
    Opdivo (nivolumab) • Yervoy (ipilimumab) • Hiltonol (poly-ICLC) • KRAS peptide vaccine
    Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer (NCT06782932)
    Phase 1/2
    Sidney Kimmel Comprehensive Cancer Center at Jo...
    Not yet recruiting
    Last update posted :
    01/20/2025
    Initiation :
    04/01/2025
    Primary completion :
    12/01/2028
    Completion :
    12/01/2028
    CD20
    |
    cyclophosphamide • balstilimab (AGEN2034) • AGEN2373 • GVAX Pancreas (allogeneic GM-CSF-secreting tumor cells) • Hiltonol (poly-ICLC) • KRAS peptide vaccine
    Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer (NCT05013216)
    Phase 1
    Sidney Kimmel Comprehensive Cancer Center at Jo...
    Recruiting
    Last update posted :
    09/04/2023
    Initiation :
    04/11/2022
    Primary completion :
    05/01/2026
    Completion :
    05/01/2026
    KRAS • BRCA1 • BRCA2 • ATM • CDKN2A • CD8 • MLH1 • MSH6 • MSH2 • CD4 • EPCAM • PMS1
    |
    KRAS mutation • PALB2 mutation • CDKN2A mutation • MLH1 mutation • PMS1 mutation
    |
    Hiltonol (poly-ICLC) • KRAS peptide vaccine