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    BIOMARKER:

    KIT D816V

    i
    Other names: KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    Entrez ID:
    3815
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    Apply
    (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis (NCT03580655)
    Phase 2
    Blueprint Medicines Corporation
    Active, not recruiting
    Last update posted :
    08/02/2023
    Initiation :
    11/21/2018
    Primary completion :
    01/31/2026
    Completion :
    01/31/2026
    TMB • KIT
    |
    KIT mutation • KIT D816V
    |
    Ayvakit (avapritinib)
    (EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies (NCT02561988)
    Phase 1
    Blueprint Medicines Corporation
    Completed
    Last update posted :
    03/17/2023
    Initiation :
    03/10/2016
    Primary completion :
    10/05/2022
    Completion :
    01/19/2023
    KIT
    |
    KIT D816V
    |
    Ayvakit (avapritinib)