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BIOMARKER:

IDH2 R172K

i
Other names: IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
Entrez ID:
Related biomarkers:
Related tests:
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
03/06/2024
Initiation :
01/30/2019
Primary completion :
07/31/2024
Completion :
07/31/2024
IDH1 • IDH2
|
IDH2 mutation • IDH1 R132H • IDH2 R172K • IDH1 R132C • IDH1 R132 • IDH1 R132G • IDH2 R140Q • IDH1 R132L • IDH1 R132S • IDH1 R132V • IDH2 R172 • IDH2 R172G
|
Lynparza (olaparib)
Phase 1
Hutchmed
Recruiting
Last update posted :
02/14/2024
Initiation :
02/28/2021
Primary completion :
09/30/2024
Completion :
06/30/2025
IDH1 • IDH2
|
IDH1 R132H • IDH2 R172K • IDH1 R132C • IDH1 R132 • IDH2 R140Q • IDH2 R172
|
HMPL-306
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
12/06/2023
Initiation :
08/04/2020
Primary completion :
12/01/2024
Completion :
12/01/2024
IDH1 • IDH2
|
IDH2 mutation • IDH1 R132H • IDH2 R172K • IDH1 R132C • IDH wild-type • IDH1 R132 • IDH1 R132G • IDH2 R140Q • IDH1 R132L • IDH1 R132S • IDH1 R132V • IDH2 R172 • IDH2 R172G
|
Lynparza (olaparib)
Phase 3
Institut de Recherches Internationales Servier
Active, not recruiting
Last update posted :
12/05/2023
Initiation :
01/05/2020
Primary completion :
09/06/2022
Completion :
08/01/2027
IDH1 • IDH2
|
IDH2 mutation • IDH1 R132H • IDH2 R172K • IDH1 R132 • IDH2 R172
|
vorasidenib (S95032)