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BIOMARKER:

HER-2 amplification + PD-L1 expression

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Other names: ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
Entrez ID:
Phase 2
Renske Altena
Suspended
Last update posted :
03/03/2021
Initiation :
05/23/2019
Primary completion :
12/01/2024
Completion :
12/01/2034
HER-2 • PD-L1 • TMB
|
PD-L1 expression • HER-2 amplification • HER-2 amplification + PD-L1 expression
|
Tecentriq (atezolizumab) • carboplatin • paclitaxel • docetaxel • Kadcyla (ado-trastuzumab emtansine) • Perjeta (pertuzumab) • epirubicin • cyclophosphamide intravenous • Herceptin Hylecta (trastuzumab/hyaluronidase-oysk)
Phase 1/2
Jiangxi Provincial Cancer Hospital
Recruiting
Last update posted :
07/22/2020
Initiation :
07/14/2020
Primary completion :
08/30/2024
Completion :
10/01/2026
HER-2
|
PD-L1 expression • HER-2 amplification • HER-2 negative • HER-2 amplification + PD-L1 expression
|
AiRuiKa (camrelizumab)
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