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DRUG:
Dupert (fulzerasib)
i
Other names:
GFH925, IBI351, GF-105 program
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News alerts, weekly reports and conference planners
Associations
(4)
News
Trials
Company:
GenFleet Therap, Innovent Biologics
Drug class:
KRAS G12C inhibitor
Related drugs:
‹
sotorasib (76)
adagrasib (35)
RG6330 (6)
D-1553 (6)
ZG19018 (4)
JAB-21822 (4)
APG-1842 (3)
ARS-1620 (2)
BI 1823911 (2)
MK-1084 (2)
JDQ443 (2)
ABSK071 (1)
AZ’8037 (1)
GEC-255 (1)
RM-029 (1)
YL-17231 (1)
D3S-001 (0)
FWD-K01 (0)
GH35 (0)
HS-10370 (0)
JNJ-74699157 (0)
LY3499446 (0)
UCT-001024 (0)
VRTX126 (0)
YL-15293 (0)
RMC-6291 (0)
LY3537982 (0)
HBI-2438 (0)
sotorasib (76)
adagrasib (35)
RG6330 (6)
D-1553 (6)
ZG19018 (4)
JAB-21822 (4)
APG-1842 (3)
ARS-1620 (2)
BI 1823911 (2)
MK-1084 (2)
JDQ443 (2)
ABSK071 (1)
AZ’8037 (1)
GEC-255 (1)
RM-029 (1)
YL-17231 (1)
D3S-001 (0)
FWD-K01 (0)
GH35 (0)
HS-10370 (0)
JNJ-74699157 (0)
LY3499446 (0)
UCT-001024 (0)
VRTX126 (0)
YL-15293 (0)
RMC-6291 (0)
LY3537982 (0)
HBI-2438 (0)
›
Associations
(4)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study of GFH925 in Combination With Cetuximab in Previously Untreated Advanced NSCLC Harboring KRAS G12C Mutation (NCT05756153)
Phase 1/2
Zhejiang Genfleet Therapeutics Co., Ltd.
Zhejiang Genfleet Therapeutics Co., Ltd.
Recruiting
Phase 1/2
Zhejiang Genfleet Therapeutics Co., Ltd.
Recruiting
Last update posted :
03/11/2024
Initiation :
04/25/2023
Primary completion :
03/01/2025
Completion :
08/01/2025
KRAS
|
KRAS mutation • KRAS G12C • KRAS G12
|
Erbitux (cetuximab) • Dupert (fulzerasib)
A Study of GFH925 in Patients With Advanced Solid Tumors With KRAS G12C Mutations (NCT05005234)
Phase 1/2
Innovent Biologics (Suzhou) Co. Ltd.
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Phase 1/2
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Last update posted :
08/16/2023
Initiation :
09/10/2021
Primary completion :
01/10/2024
Completion :
04/10/2024
KRAS
|
KRAS mutation • KRAS G12C • KRAS G12
|
Dupert (fulzerasib)
Efficacy and Safety of IBI351 in Combination With Sintilimab ± Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation (NCT05504278)
Phase 1
Innovent Biologics (Suzhou) Co. Ltd.
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Phase 1
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Last update posted :
05/29/2023
Initiation :
09/20/2022
Primary completion :
05/12/2024
Completion :
07/31/2027
KRAS
|
KRAS mutation • KRAS G12C • KRAS G12
|
Erbitux (cetuximab) • carboplatin • Tyvyt (sintilimab) • pemetrexed • Dupert (fulzerasib)
A Study of IBI351 in Combination With Cetuximab in Subjects With KRAS G12C Mutated Metastatic Colorectal Cancer (NCT05497336)
Phase 1
Innovent Biologics (Suzhou) Co. Ltd.
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Phase 1
Innovent Biologics (Suzhou) Co. Ltd.
Recruiting
Last update posted :
09/30/2022
Initiation :
08/18/2022
Primary completion :
08/30/2023
Completion :
09/30/2024
KRAS
|
KRAS mutation • KRAS G12C • KRAS G12
|
Erbitux (cetuximab) • Dupert (fulzerasib)
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