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DRUG:
Epratucyn (epratuzumab)
i
Other names:
hCD22, IMMU LL2, MOAB LL2, AMG 412, IMMU 103, hLL2
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Associations
News
Trials
Company:
Gilead
Drug class:
CD22 inhibitor
Related drugs:
‹
BL-22 (0)
Imtox19/Imtox22 (0)
IgG-RFB4-SMPT-dgA (0)
epratuzumab Y-90 (0)
REGN5837 (0)
YT-19/22 (0)
anti CD19/CD22 CAR NK cells (0)
TAC-001 (0)
JNJ-8780 (0)
BL-22 (0)
Imtox19/Imtox22 (0)
IgG-RFB4-SMPT-dgA (0)
epratuzumab Y-90 (0)
REGN5837 (0)
YT-19/22 (0)
anti CD19/CD22 CAR NK cells (0)
TAC-001 (0)
JNJ-8780 (0)
›
Associations
News
Trials
Phase
Status
Apply
Phase
Status
Apply
International Study for Treatment of Standard Risk Childhood Relapsed ALL 2010 (IntReALL SR 2010) (NCT01802814)
Phase 3
Charite University, Berlin, Germany
Charite University, Berlin, Germany
Completed
Phase 3
Charite University, Berlin, Germany
Completed
Last update posted :
02/09/2024
Initiation :
05/01/2014
Primary completion :
07/31/2023
Completion :
07/31/2023
CD22
|
CD22 expression
|
Epratucyn (epratuzumab)
Monoclonal Antibody Therapy and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma (NCT00301821)
Phase 2
Alliance for Clinical Trials in Oncology
Alliance for Clinical Trials in Oncology
Completed
Phase 2
Alliance for Clinical Trials in Oncology
Completed
Last update posted :
10/09/2019
Initiation :
01/01/2006
Primary completion :
10/01/2008
Completion :
04/01/2015
CD20 • CD22
|
Rituxan (rituximab) • doxorubicin hydrochloride • cyclophosphamide • vincristine • prednisone • Epratucyn (epratuzumab)
Multi-centric Study (CHEPRALL) (NCT01219816)
Phase 2
Nantes University Hospital
Nantes University Hospital
Completed
Phase 2
Nantes University Hospital
Completed
Last update posted :
02/27/2018
Initiation :
11/01/2010
Primary completion :
11/01/2016
Completion :
11/01/2016
CD22
|
CD22 expression
|
doxorubicin hydrochloride • cyclophosphamide • vincristine • Epratucyn (epratuzumab)
Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL) (NCT00098839)
Phase 2
Children's Oncology Group
Children's Oncology Group
Completed
Phase 2
Children's Oncology Group
Completed
Last update posted :
12/12/2017
Initiation :
02/01/2005
Primary completion :
04/01/2011
Completion :
04/01/2011
CD22
|
CD22 expression
|
cytarabine • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • prednisone • leucovorin calcium • Oncaspar liquid (pegaspargase) • Marqibo (vincristine liposomal) • Epratucyn (epratuzumab) • Neupogen (filgrastim) • cyclophosphamide intravenous • dexrazoxane
S0910 Epratuzumab, Cytarabine, and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (NCT00945815)
Phase 2
Southwest Oncology Group
Southwest Oncology Group
Completed
Phase 2
Southwest Oncology Group
Completed
Last update posted :
11/06/2017
Initiation :
09/01/2010
Primary completion :
03/01/2013
Completion :
08/01/2017
CD22 • CD33 • CD4 • ANPEP
|
cytarabine • clofarabine • Epratucyn (epratuzumab)
Testing a Reduced Conditioning Regimen FB2A2 Preceded by a Fractionated Radio-immunotherapy (RIT) With 90Y-Epratuzumab Before Allogeneic Stem Cell Transplantation for Patients With Lymphocyte B CD22 Positive Acute Lymphoblastic Leukemia (EPRALLO) (NCT02577094)
Phase 1/2
Nantes University Hospital
Nantes University Hospital
Withdrawn
Phase 1/2
Nantes University Hospital
Withdrawn
Last update posted :
01/19/2017
Primary completion :
01/01/2017
Completion :
01/01/2017
CD22
|
CD22 expression
|
fludarabine IV • busulfan • Epratucyn (epratuzumab) • LymphoCide Y-90 (epratuzumab Y-90)
Epratuzumab and Rituximab in Treating Patients With Previously Untreated Follicular Non-Hodgkin Lymphoma (NCT00553501)
Phase 2
Alliance for Clinical Trials in Oncology
Alliance for Clinical Trials in Oncology
Completed
Phase 2
Alliance for Clinical Trials in Oncology
Completed
Last update posted :
07/06/2016
Initiation :
03/01/2008
Primary completion :
07/01/2010
Completion :
07/01/2014
CD20 • CD4
|
Rituxan (rituximab) • Epratucyn (epratuzumab)
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