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DRUG:
elgemtumab (LJM-716)
i
Other names:
LJM-716, LJM716, NOV-6
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News alerts, weekly reports and conference planners
Associations
(1)
News
Trials
Company:
Novartis
Drug class:
HER3 inhibitor
Related drugs:
‹
zenocutuzumab-zbco (16)
MM-121 (12)
Ac-225 ErbB3 targeted radiotherapy (4)
ISU104 (4)
AV-203 (1)
SI-B001 (1)
U3-1287 (1)
177Lu-HER3 ARC (0)
CDX-3379 (0)
GSK2849330 (0)
MM 111 (0)
Sym013 (0)
INCB7839 (0)
MEHD7945A (0)
MM-141 (0)
RG7116 (0)
AZD8931 (0)
zenocutuzumab-zbco (16)
MM-121 (12)
Ac-225 ErbB3 targeted radiotherapy (4)
ISU104 (4)
AV-203 (1)
SI-B001 (1)
U3-1287 (1)
177Lu-HER3 ARC (0)
CDX-3379 (0)
GSK2849330 (0)
MM 111 (0)
Sym013 (0)
INCB7839 (0)
MEHD7945A (0)
MM-141 (0)
RG7116 (0)
AZD8931 (0)
›
Associations
(1)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Open-Label Study Evaluating the Safety and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer (NCT02167854)
Phase 1
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
Completed
Phase 1
Memorial Sloan Kettering Cancer Center
Completed
Last update posted :
07/09/2021
Initiation :
06/16/2014
Primary completion :
07/07/2021
Completion :
07/07/2021
HER-2 • PIK3CA
|
HER-2 amplification • PIK3CA mutation
|
Herceptin (trastuzumab) • Piqray (alpelisib) • elgemtumab (LJM-716)
A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer (NCT01598077)
Phase 1
Novartis Pharmaceuticals
Novartis Pharmaceuticals
Completed
Phase 1
Novartis Pharmaceuticals
Completed
Last update posted :
12/19/2020
Initiation :
07/01/2012
Primary completion :
03/01/2014
Completion :
03/01/2014
HER-2
|
elgemtumab (LJM-716)
A Phase I Study of LJM716 in Japanese Patients With Advanced Solid Tumors (NCT01911936)
Phase 1
Novartis Pharmaceuticals
Novartis Pharmaceuticals
Completed
Phase 1
Novartis Pharmaceuticals
Completed
Last update posted :
12/17/2020
Initiation :
09/01/2013
Primary completion :
03/01/2015
Completion :
03/01/2015
HER-2
|
HER-2 overexpression
|
elgemtumab (LJM-716)
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