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DRUG:
ifinatamab deruxtecan (DS-7300)
i
Other names:
DS-7300, DS7300, DS 7300, DS-7300a, anti-B7-H3/DXd ADC, MABX-9001a/DXd ADC, anti-B7H3 antibody+MAAA-1181a, B7-H3 DXd-ADC, I-Dxd, MK-2400, DS7300a, DS 7300a, IDxd, I Dxd, MK2400, MK 2400
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News alerts, weekly reports and conference planners
Associations
(5)
News
Trials
Company:
Daiichi Sankyo, Merck (MSD)
Drug class:
Topoisomerase I inhibitor, B7-H3-targeted antibody-drug conjugate
Related drugs:
‹
fam-trastuzumab deruxtecan-nxki (90)
irinotecan (48)
U3-1402 (28)
sacituzumab govitecan-hziy (17)
topotecan (16)
SHR-A1811 (15)
datopotamab deruxtecan (11)
DM001 (6)
AZD8205 (5)
AMB302 (4)
DB-1310 (4)
DM002 (4)
BNT323 (4)
BL-M07D1 (3)
DS-6157 (3)
HRA00129-C004 (3)
sacituzumab tirumotecan (3)
nanoliposomal irinotecan (3)
PLX038 (3)
ABBV-400 (3)
CUSP06 (2)
DAN-222 (2)
DM005 (2)
PRO1102 (2)
SSH20 (2)
IMMU-130 (2)
AZD9592 (2)
AMT-562 (1)
BAT8008 (1)
BL-M02D1 (1)
BNT324 (1)
camptothecin nanosomal (1)
DAN-311 (1)
ELU001 (1)
HMBD-501 (1)
IMMU-140 (1)
IT-141 (1)
OBI-992 (1)
OQY-3258 (1)
PF-08046044 (1)
rinatabart sesutecan (1)
SGN-CD30C (1)
SHR-A2102 (1)
STRO-003 (1)
ZW191 (1)
ZW220 (1)
ZW251 (1)
IBI-343 (1)
BL-B01D1 (1)
AZD5335 (1)
ABBV-706 (0)
ARC-401 (0)
BAT8007 (0)
BAT8010 (0)
BL-M11D1 (0)
BNT326 (0)
CEB-01 (0)
CPO301 (0)
belotecan (0)
DS-3939 (0)
FZ-AD004 (0)
GEN1160 (0)
GSK5733584 (0)
GSK5764227 (0)
HA-irinotecan (0)
HLX43 (0)
IBI-130 (0)
IBI-354 (0)
ICAM‑1 ADC (0)
LMP744 (0)
LY4170156 (0)
lentinan (0)
TLC388 (0)
MHB036C (0)
MHB088C (0)
NK012 (0)
etirinotecan pegol (0)
SHR-A1912 (0)
SKB315 (0)
TQB2102 (0)
TQB2103 (0)
VIP236 (0)
YL201 (0)
CBX-12 (0)
JSKN003 (0)
EP0057 (0)
SHR-A1904 (0)
LMP400 (0)
HR070803 (0)
irinotecan liposomal (0)
LY01616 (0)
FF-10850 (0)
PEN-866 (0)
SSS22 (0)
M9140 (0)
DS-6000 (0)
SHR-A2009 (0)
simmitecan (0)
SHR-A1921 (0)
topotecan episcleral (0)
MGC018 (5)
ITC-6102RO (2)
ABBV-155 (0)
fam-trastuzumab deruxtecan-nxki (90)
irinotecan (48)
U3-1402 (28)
sacituzumab govitecan-hziy (17)
topotecan (16)
SHR-A1811 (15)
datopotamab deruxtecan (11)
DM001 (6)
AZD8205 (5)
AMB302 (4)
DB-1310 (4)
DM002 (4)
BNT323 (4)
BL-M07D1 (3)
DS-6157 (3)
HRA00129-C004 (3)
sacituzumab tirumotecan (3)
nanoliposomal irinotecan (3)
PLX038 (3)
ABBV-400 (3)
CUSP06 (2)
DAN-222 (2)
DM005 (2)
PRO1102 (2)
SSH20 (2)
IMMU-130 (2)
AZD9592 (2)
AMT-562 (1)
BAT8008 (1)
BL-M02D1 (1)
BNT324 (1)
camptothecin nanosomal (1)
DAN-311 (1)
ELU001 (1)
HMBD-501 (1)
IMMU-140 (1)
IT-141 (1)
OBI-992 (1)
OQY-3258 (1)
PF-08046044 (1)
rinatabart sesutecan (1)
SGN-CD30C (1)
SHR-A2102 (1)
STRO-003 (1)
ZW191 (1)
ZW220 (1)
ZW251 (1)
IBI-343 (1)
BL-B01D1 (1)
AZD5335 (1)
ABBV-706 (0)
ARC-401 (0)
BAT8007 (0)
BAT8010 (0)
BL-M11D1 (0)
BNT326 (0)
CEB-01 (0)
CPO301 (0)
belotecan (0)
DS-3939 (0)
FZ-AD004 (0)
GEN1160 (0)
GSK5733584 (0)
GSK5764227 (0)
HA-irinotecan (0)
HLX43 (0)
IBI-130 (0)
IBI-354 (0)
ICAM‑1 ADC (0)
LMP744 (0)
LY4170156 (0)
lentinan (0)
TLC388 (0)
MHB036C (0)
MHB088C (0)
NK012 (0)
etirinotecan pegol (0)
SHR-A1912 (0)
SKB315 (0)
TQB2102 (0)
TQB2103 (0)
VIP236 (0)
YL201 (0)
CBX-12 (0)
JSKN003 (0)
EP0057 (0)
SHR-A1904 (0)
LMP400 (0)
HR070803 (0)
irinotecan liposomal (0)
LY01616 (0)
FF-10850 (0)
PEN-866 (0)
SSS22 (0)
M9140 (0)
DS-6000 (0)
SHR-A2009 (0)
simmitecan (0)
SHR-A1921 (0)
topotecan episcleral (0)
MGC018 (5)
ITC-6102RO (2)
ABBV-155 (0)
›
Associations
(5)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001) (NCT04471727)
Phase 1/2
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Harpoon Therapeutics, Inc., a subsidiar...
Recruiting
Phase 1/2
Harpoon Therapeutics, Inc., a subsidiary of Mer...
Recruiting
Last update posted :
02/20/2025
Initiation :
12/14/2020
Primary completion :
06/30/2027
Completion :
06/30/2027
DLL3
|
DLL3 expression
|
Tecentriq (atezolizumab) • ifinatamab deruxtecan (DS-7300) • gocatamig (MK-6070)
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